2. Gene
  3. PEX11A - peroxisomal biogenesis factor 11 alpha Gene

PEX11A - peroxisomal biogenesis factor 11 alpha Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：过氧化物酶体生物发生因子 11 α

种属: Homo sapiens

同用名: PMP28; hsPEX11p; PEX11alpha; PEX11-ALPHA

基因 ID: 8800 | 基因类型: protein coding

关于 PEX11A

Cytogenetic location: 15q26.1 Genomic coordinates (GRCh38): 15:89,681,535-89,690,754 (from NCBI)

This gene has 5 transcripts (splice variants), 201 orthologues and 1 paralogue. Ubiquitous expression in fat (RPKM 14.4), prostate (RPKM 9.1) and 24 other tissues.

功能概要

该基因是 PEX11 家族的成员，该家族由参与调节过氧化物酶体维持和增殖的膜延长因子组成。该基因产物与过氧化物酶体膜蛋白 19 相互作用，并可能响应外部刺激以增加过氧化物酶体丰度。已经观察到该基因编码多种亚型的可变剪接转录物变体。[RefSeq 提供，2012 年 10 月]

This gene is a member of the PEX11 family, which is composed of membrane elongation factors involved in regulation of peroxisome maintenance and proliferation. This gene product interacts with peroxisomal membrane protein 19 and may respond to outside stimuli to increase peroxisome abundance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]

PEX11A 基因产物(3)

mRNA Protein Name
NM_001271572.2 NP_001258501.1 peroxisomal membrane protein 11A isoform 2
NM_001271573.2 NP_001258502.1 peroxisomal membrane protein 11A isoform 3
NM_003847.3 NP_003838.1 peroxisomal membrane protein 11A isoform 1

PEX11A 蛋白结构

PEX11

PEX11: Peroxisomal biogenesis factor 11 (PEX11) (1 - 237)

  • 0
  • 100
  • 200
  • 247 a.a.
蛋白主名 其他名称

peroxisomal membrane protein 11A

28 kDa peroxisomal integral membrane protein

重组 PEX11A 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77133 PEX11A Protein, Human (HEK293, Fc) O75192 (R106-P219) ≥95%

关联疾病

疾病名称 别名
Peroxisomal Acyl-Coa Oxidase Deficiency

Pseudoneonatal Adrenoleukodystrophy

Straight-Chain Acyl-Coa Oxidase Deficiency

Pseudoadrenoleukodystrophy

PSEUDO-NALD

Pseudo-Neonatal Adrenoleukodystrophy

Acyl-Coa Oxidase Deficiency

Peroxisomal Acyl-Coenzyme A Oxidase

Acyl-Coenzyme A Oxidase Deficiency

Adrenoleukodystrophy, Pseudoneonatal

Deficiency, Peroxisomal Acyl-Coa Oxidase
Peroxisomal Biogenesis Disorder

Zellweger Spectrum Disorders

Peroxisome Biogenesis Disorder-Zellweger Syndrome Spectrum

Disorders Of Peroxisome Biogenesis

Zellweger Spectrum

Zellweger Syndrome Spectrum

Peroxisomal Biogenesis Disorders

Pbd, Zss

Pbd-Zsd

Pbd-Zss

Pbd-Zellweger Spectrum Disorder

Peroxisomal Biogenesis Disorders, Zellweger Syndrome Spectrum

Peroxisome Biogenesis Disorder

Peroxisome Biogenesis Disorder Spectrum

Peroxisome Biogenesis Disorders

Zellweger Spectrum Disorder

Hyperpipecolic Acidaemia
Refsum Disease, Classic

Refsum Disease

Heredopathia Atactica Polyneuritiformis

Phytanic Acid Oxidase Deficiency

Hmsn Iv

Refsum Disease, Adult, 1

Refsum'S Disease

Phytanic Acid Storage Disease

Hereditary Motor And Sensory Neuropathy Iv

Hmsn4

Hmsn Type Iv

Hmsn 4

Adult Refsum Disease

Classic Refsum Disease

Hereditary Motor And Sensory Neuropathy Type Iv

Refsum Syndrome

Hsmn Iv

Disorder Of Cornification 11

Doc 11

Hereditary Sensory And Motor Neuropathy Type 4

Hypertrophic Neuropathy Of Refsum

Ard

Crd

Hereditary Motor And Sensory Neuropathy Type 4

Phytanic-Coa Hydroxylase Deficiency

RD
Peroxisomal Disease

Peroxisomal Disorder

Peroxisomal Disorders

Peroxisomal Defects
Acatalasemia

Acatalasia

Catalase Deficiency

Deficiency Of Catalase

ACATLAS

Takahara'S Disease

Takahara Disease
Peroxisome Biogenesis Disorder 1b

Peroxisome Biogenesis Disorder

Infantile Refsum Disease

Infantile Phytanic Acid Storage Disease

PBD1B

Refsum Disease, Infantile

Adrenoleukodystrophy, Autosomal Neonatal

Ird

Mild Pbd-Zsd

Mild Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder

Pbd-Zsd

Peroxisome Biogenesis Disorder Spectrum

Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder

Autosomal Neonatal Adrenoleukodystrophy

Refsum Disease Infantile

Peroxisome Biogenesis Disorders

Peroxisome Biogenesis Disorder, Type 1b
Rhizomelic Chondrodysplasia Punctata

Chondrodysplasia Punctata, Rhizomelic

Rcdp

Chondrodysplasia Punctata, Rhizomelic Form

Rcp

Chondrodysplasia Punctata Rhizomelic
Zellweger Syndrome

Cerebrohepatorenal Syndrome

Zellweger Leukodystrophy

Zs

Congenital Iron Overload

Chr

Zws

Severe Pbd-Zsd

Severe Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10341 PEX11A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PEX11A RGD RGD:619842
Felis catus PEX11A VGNC VGNC:104575
Macaca mulatta PEX11A VGNC VGNC:75946
Canis familiaris PEX11A VGNC VGNC:44426
Mus musculus PEX11A MGD MGI:1338788
Others PEX11A NCBI
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