2. Gene
  3. CDKL1 - cyclin dependent kinase like 1 Gene

CDKL1 - cyclin dependent kinase like 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：细胞周期蛋白依赖性激酶样 1

种属: Homo sapiens

同用名: P42; KKIALRE

基因 ID: 8814 | 基因类型: protein coding

关于 CDKL1

Cytogenetic location: 14q21.3 Genomic coordinates (GRCh38): 14:50,326,265-50,397,298 (from NCBI)

This gene has 11 transcripts (splice variants), 194 orthologues and 26 paralogues. Ubiquitous expression in kidney (RPKM 3.9), endometrium (RPKM 2.6) and 24 other tissues.

功能概要

该基因产物是主要在细胞核中积累的 CDC2 相关丝氨酸/苏氨酸蛋白激酶大家族的成员。[RefSeq 提供，2018 年 11 月]

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. [provided by RefSeq, Nov 2018]

CDKL1 基因产物(4)

mRNA Protein Name
NM_001282236.2 NP_001269165.1 cyclin-dependent kinase-like 1 isoform 2
NM_001367064.1 NP_001353993.1 cyclin-dependent kinase-like 1 isoform 3
NM_001367065.1 NP_001353994.1 cyclin-dependent kinase-like 1 isoform 3
NM_004196.7 NP_004187.3 cyclin-dependent kinase-like 1 isoform 1

CDKL1 蛋白结构

Pkinase

Pkinase: Protein kinase domain (5 - 288)

  • 0
  • 100
  • 200
  • 300
  • 358 a.a.
蛋白主名 其他名称

cyclin-dependent kinase-like 1

cyclin-dependent kinase-like 1 (CDC2-related kinase)

关联疾病

疾病名称 别名
Gene Duplication Disease

Gene Duplication Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02405 CDKL1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus CDKL1 VGNC VGNC:27138
Felis catus CDKL1 VGNC VGNC:60708
Canis familiaris CDKL1 VGNC VGNC:39064
Mus musculus CDKL1 MGD MGI:1918341
Macaca mulatta CDKL1 VGNC VGNC:70986
Rattus norvegicus CDKL1 RGD RGD:1305080
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