2. Gene
  3. PGLYRP1 - peptidoglycan recognition protein 1 Gene

PGLYRP1 - peptidoglycan recognition protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肽聚糖识别蛋白 1

种属: Homo sapiens

同用名: PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L

基因 ID: 8993 | 基因类型: protein coding

关于 PGLYRP1

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:46,019,153-46,023,053 (from NCBI)

This gene has 1 transcript (splice variant), 184 orthologues and 3 paralogues. Restricted expression toward bone marrow (RPKM 135.5).

功能概要

启用肽聚糖结合活性和肽聚糖免疫受体活性。参与抗菌肽介导的抗菌体液免疫反应；杀死其他生物体的细胞；和对细菌的反应。位于细胞外外泌体。 [由基因组资源联盟提供，2022 年 4 月]

Enables peptidoglycan binding activity and peptidoglycan immune receptor activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide; killing of cells of Other organism; and response to bacterium. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PGLYRP1 基因产物(1)

mRNA Protein Name
NM_005091.3 NP_005082.1 peptidoglycan recognition protein 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Hsp70 protein binding IDA
IDA: 通过直接分析推断
14585845 GOA
enables molecular adaptor activity IDA
IDA: 通过直接分析推断
26654597 GOA
enables peptidoglycan binding IDA
IDA: 通过直接分析推断
11461926 GOA
enables peptidoglycan immune receptor activity IDA
IDA: 通过直接分析推断
11461926 GOA
enables receptor ligand activity IDA
IDA: 通过直接分析推断
25595774 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in antimicrobial humoral immune response mediated by antimicrobial peptide IDA
IDA: 通过直接分析推断
16354652 GOA
involved in defense response to Gram-positive bacterium IDA
IDA: 通过直接分析推断
11461926 GOA
involved in detection of bacterium IDA
IDA: 通过直接分析推断
11461926 GOA
involved in killing of cells of another organism IDA
IDA: 通过直接分析推断
16354652 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in extracellular space IDA
IDA: 通过直接分析推断
14585845 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PGLYRP1 蛋白结构

Amidase_2

Amidase_2: N-acetylmuramoyl-L-alanine amidase (52 - 181)

  • 0
  • 100
  • 196 a.a.
蛋白主名 其他名称

peptidoglycan recognition protein 1

TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein)

重组 PGLYRP1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78014 PGLYRP1/PGRP-S Protein, Human (HEK293, Fc) O75594 (Q22-P196) ≥95%

关联疾病

疾病名称 别名
Retinitis Pigmentosa 86

RP86

Retinitis Pigmentosa, Type 86
Immunodeficiency 60

Bach2-Related Immunodeficiency And Autoimmunity

Brida

Imd60
Psoriasis 4

PSORS4

Psoriasis Susceptibility 4

Psoriasis 4, Susceptibility To
Bacterial Infectious Disease

Bacterial Infections

Bacterial Infection Nos

Disease Caused By Bacteria

Bacterial Disease Or Disorder
Mite Infestation

Mite Infestations

Acariasis

Infestation By Mites Nos
Trombiculiasis
Parasitic Ectoparasitic Infectious Disease

Ectoparasitic Infestations

Ectoparasitism
Trench Fever

His-Werner Disease

Quintan Fever

Shin Bone Fever

Wolhynian Fever

Tibialgic Fever

Bartonellosis Due To Bartonella Quintana Infection

Febris Quintata

Five Day Fever

Fever Due To Rickettsia Quintana

Febris Quintana

Fever Due To Bartonella Quintana

Fever Due To Rochalimaea Quintana

Meuse Fever
Cicatricial Entropion
Sveinsson Chorioretinal Atrophy

SCRA

Atrophia Areata

Helicoid Peripapillary Chorioretinal Degeneration

Hpcd

Aa

Peripapillary Chorioretinal Degeneration, Icelandic Type

Helicoidal Peripapillary Chorioretinal Degeneration

Atrophy, Chorioretinal, Sveinsson
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10387 PGLYRP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus PGLYRP1 MGD MGI:1345092
Macaca mulatta PGLYRP1 VGNC VGNC:75968
Bos taurus PGLYRP1 VGNC VGNC:32791
Rattus norvegicus PGLYRP1 RGD RGD:621429
Felis catus PGLYRP1 VGNC VGNC:68817
Canis familiaris PGLYRP1 VGNC VGNC:44461
Others PGLYRP1 NCBI
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