PKDCC - protein kinase domain containing, cytoplasmic Gene

中文名称：含蛋白激酶结构域，细胞质

种属: Homo sapiens

同用名: Vlk; RLSDF; SGK493

基因 ID: 91461 | 基因类型: protein coding

关于 PKDCC

Cytogenetic location: 2p21 Genomic coordinates (GRCh38): 2:42,048,021-42,058,517 (from NCBI)

This gene has 9 transcripts (splice variants), 156 orthologues, 2 paralogues and is associated with 1 phenotype. Broad expression in ovary (RPKM 28.2), endometrium (RPKM 26.6) and 22 other tissues.

功能概要

启用非跨膜蛋白酪氨酸激酶活性。参与肽酰酪氨酸磷酸化和骨骼系统发育。位于胞外区。 [由基因组资源联盟提供，2022 年 4 月]

Enables non-membrane spanning protein tyrosine kinase activity. Involved in peptidyl-tyrosine phosphorylation and skeletal system development. Located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PKDCC 基因产物(1)

mRNA	Protein	Name
NM_138370.3	NP_612379.2	extracellular tyrosine-protein kinase PKDCC precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables non-membrane spanning protein tyrosine kinase activity	IDA IDA: 通过直接分析推断	25171405	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in peptidyl-tyrosine phosphorylation	IDA IDA: 通过直接分析推断	25171405	GOA
involved in skeletal system development	IMP IMP: 通过突变表型推断	30478137	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in extracellular region	IDA IDA: 通过直接分析推断	25171405	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PKDCC 蛋白结构

PIP49_C

0
100
200
300
400
493 a.a.

蛋白主名

其他名称

extracellular tyrosine-protein kinase PKDCC

protein kinase domain containing, cytoplasmic homolog

关联疾病

疾病名称

别名

Rhizomelic Limb Shortening With Dysmorphic Features

RLSDF

N Syndrome

NSX	Intellectual Disability, Malformations, Chromosome Breakage, And Development Of T-Cell Leukemia

Amelogenesis Imperfecta, Type Ic

Amelogenesis Imperfecta Type 1c	AI1C
Amelogenesis Imperfecta Type Ic	Amelogenesis Imperfecta, Local Hypoplastic Type, Autosomal Recessive
Amelogenesis Imperfecta, Hypoplastic, With Or Without Open-Bite Malocclusion, Autosomal Recessive	Autosomal Recessive Amelogenesis Imperfecta Hypoplastic With Or Without Openbite Malocclusion
Autosomal Recessive Amelogenesis Imperfecta Local Hypoplastic Type	Amelogenesis Imperfecta 1c
Amelogenesis Imperfecta Hypoplastic With Or Without Openbite Malocclusion Autosomal Recessive	Amelogenesis Imperfecta Local Hypoplastic Type Autosomal Recessive

Cleft Palate, Isolated

Cleft Palate	Isolated Cleft Palate
CPI	Cp
Palatoschisis	Cleft Palate Isolated
Uranostaphyloschisis	Congenital Fissure Of Palate
Cleft Of Secondary Palate

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS10595	PKDCC Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	PKDCC	VGNC	VGNC:81149
Macaca mulatta	PKDCC	VGNC	VGNC:106196
Canis familiaris	PKDCC	VGNC	VGNC:44603
Mus musculus	PKDCC	MGD	MGI:2147077
Bos taurus	PKDCC	VGNC	VGNC:32938
Rattus norvegicus	PKDCC	RGD	RGD:1311939

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

PKDCC - protein kinase domain containing, cytoplasmic Gene

关于 PKDCC

功能概要

PKDCC 基因产物(1)

PKDCC 蛋白结构

关联疾病

直系同源

热门区域

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PKDCC - protein kinase domain containing, cytoplasmic Gene

关于 PKDCC

功能概要

PKDCC 基因产物(1)

PKDCC 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z