2. Gene
  3. SLC28A1 - solute carrier family 28 member 1 Gene

SLC28A1 - solute carrier family 28 member 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 28 成员 1

种属: Homo sapiens

同用名: CNT1; HCNT1; URCTU

基因 ID: 9154 | 基因类型: protein coding

关于 SLC28A1

Cytogenetic location: 15q25.3 Genomic coordinates (GRCh38): 15:84,884,662-84,975,649 (from NCBI)

This gene has 4 transcripts (splice variants), 198 orthologues, 2 paralogues and is associated with 1 phenotype. Biased expression in kidney (RPKM 9.5), small intestine (RPKM 9.4) and 2 other tissues.

功能概要

启用唑类跨膜转运蛋白活性；胞苷跨膜转运蛋白活性；和尿苷跨膜转运蛋白活性。参与唑类跨膜转运；核苷运输；和含嘧啶的化合物跨膜转运。位于胞质溶胶中；核斑点；和质膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables azole transmembrane transporter activity; cytidine transmembrane transporter activity; and uridine transmembrane transporter activity. Involved in azole transmembrane transport; nucleoside transport; and pyrimidine-containing compound transmembrane transport. Located in cytosol; nuclear speck; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC28A1 基因产物(6)

mRNA Protein Name
NM_001287761.2 NP_001274690.1 sodium/nucleoside cotransporter 1 isoform 3
NM_001287762.2 NP_001274691.1 sodium/nucleoside cotransporter 1 isoform 1
NM_001321721.2 NP_001308650.1 sodium/nucleoside cotransporter 1 isoform 4
NM_001321722.2 NP_001308651.1 sodium/nucleoside cotransporter 1 isoform 5
NM_004213.5 NP_004204.3 sodium/nucleoside cotransporter 1 isoform 1
NM_201651.3 NP_964014.1 sodium/nucleoside cotransporter 1 isoform 2

SLC28A1 蛋白结构

Nucleos_tra2_N

Nucleos_tra2_N: Na+ dependent nucleoside transporter N-terminus (184 - 255)

Gate

Gate: Nucleoside recognition (264 - 359)

Nucleos_tra2_C

Nucleos_tra2_C: Na+ dependent nucleoside transporter C-terminus (367 - 590)

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  • 649 a.a.
蛋白主名 其他名称

sodium/nucleoside cotransporter 1

Na(+)/nucleoside cotransporter 1

关联疾病

疾病名称 别名
Uridine-Cytidineuria

URCTU
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13150 SLC28A1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus SLC28A1 VGNC VGNC:34791
Rattus norvegicus SLC28A1 RGD RGD:621223
Felis catus SLC28A1 VGNC VGNC:65294
Mus musculus SLC28A1 MGD MGI:3605073
Macaca mulatta SLC28A1 VGNC VGNC:77444
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