1. Gene
  2. CD5L - CD5 molecule like Gene

CD5L - CD5 molecule like Gene

中文名称:CD5 分子样

种属: Homo sapiens

同用名: AIM; API6; CT-2; hAIM; PRO229; Spalpha; SP-ALPHA

基因 ID: 922 | 基因类型: protein coding

关于 CD5L

Cytogenetic location: 1q23.1 Genomic coordinates (GRCh38): 1:157,827,068-157,841,808 (from NCBI)

This gene has 2 transcripts (splice variants), 371 orthologues and 15 paralogues. Restricted expression toward spleen (RPKM 260.3).

功能概要

预测启用丝氨酸型内肽酶活性。预计参与酶原激活。预计在补体依赖性细胞毒性和补体激活调节的正调节上游或正调节内起作用。位于细胞表面。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Predicted to act upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Located in cell surface. [provided by Alliance of Genome Resources, Apr 2022]

CD5L 基因产物(2)

mRNA Protein Name
NM_001347698.2 NP_001334627.1 CD5 antigen-like isoform 2 precursor
NM_005894.3 NP_005885.1 CD5 antigen-like isoform 1 precursor
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
25284781 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CD5L 蛋白结构

SRCR

SRCR: Scavenger receptor cysteine-rich domain (27 - 125)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (142 - 239)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (247 - 346)

  • 0
  • 100
  • 200
  • 300
  • 347 a.a.
蛋白主名 其他名称

CD5 antigen-like

CD5 antigen-like (scavenger receptor cysteine rich family)

重组 CD5L 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72718 CD5L Protein, Human (HEK293, His) O43866 (S20-G347) ≥95%

关联疾病

疾病名称 别名
Hereditary Elliptocytosis

Congenital Elliptocytosis

Ovalocytosis

Elliptocytosis, Hereditary

He

Elliptocytosis Hereditary

Congenital Ovalocytosis

Elliptocytosis

Hereditary Elliptocytosis With Infantile Poikilocytosis

Hereditary Ovalocytosis

Oval Erythrocytosis

He - [Hereditary Elliptocytosis]

Elliptocytosis Anaemia

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus CD5L VGNC VGNC:60634
Rattus norvegicus CD5L RGD RGD:1308526
Mus musculus CD5L MGD MGI:1334419
Canis familiaris CD5L VGNC VGNC:38965
Bos taurus CD5L VGNC VGNC:54903
Macaca mulatta CD5L VGNC VGNC:70774
Others CD5L NCBI