1. Gene
  2. STK17B - serine/threonine kinase 17b Gene

STK17B - serine/threonine kinase 17b Gene

中文名称:丝氨酸/苏氨酸激酶 17b

种属: Homo sapiens

同用名: DRAK2

基因 ID: 9262 | 基因类型: protein coding

关于 STK17B

Cytogenetic location: 2q32.3 Genomic coordinates (GRCh38): 2:196,133,583-196,176,483 (from NCBI)

This gene has 5 transcripts (splice variants), 202 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 54.0), lymph node (RPKM 45.0) and 18 other tissues.

功能概要

启用 ATP 结合活性和蛋白丝氨酸/苏氨酸激酶活性。参与细胞内信号转导;成纤维细胞凋亡过程的正向调控;和蛋白质磷酸化。位于核内。 [由基因组资源联盟提供,2022 年 4 月]

Enables ATP binding activity and protein serine/threonine kinase activity. Involved in intracellular signal transduction; positive regulation of fibroblast apoptotic process; and protein phosphorylation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

STK17B 基因产物(1)

mRNA Protein Name
NM_004226.4 NP_004217.1 serine/threonine-protein kinase 17B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
9786912 GOA
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
9786912 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular signal transduction IDA
IDA: 通过直接分析推断
9786912 GOA
involved in positive regulation of fibroblast apoptotic process IMP
IMP: 通过突变表型推断
9786912 GOA
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
9786912 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9786912 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

STK17B 蛋白结构

Pkinase

Pkinase: Protein kinase domain (36 - 293)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase 17B

DAP kinase-related apoptosis-inducing protein kinase 2

关联疾病

疾病名称 别名
Colon Squamous Cell Carcinoma

Colonic Epidermoid Carcinoma

Squamous Cell Carcinoma Of Colon

Squamous Cell Carcinoma Of The Colon

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus STK17B VGNC VGNC:65778
Mus musculus STK17B MGD MGI:2138162
Macaca mulatta STK17B VGNC VGNC:110332
Rattus norvegicus STK17B RGD RGD:620457
Canis familiaris STK17B VGNC VGNC:46908
Bos taurus STK17B VGNC VGNC:35388
Others STK17B NCBI