1. Gene
  2. STK17A - serine/threonine kinase 17a Gene

STK17A - serine/threonine kinase 17a Gene

中文名称:丝氨酸/苏氨酸激酶 17a

种属: Homo sapiens

同用名: DRAK1

基因 ID: 9263 | 基因类型: protein coding

关于 STK17A

Cytogenetic location: 7p13 Genomic coordinates (GRCh38): 7:43,583,108-43,627,379 (from NCBI)

This gene has 4 transcripts (splice variants), 187 orthologues and 1 paralogue. Broad expression in lymph node (RPKM 25.5), bone marrow (RPKM 15.3) and 24 other tissues.

功能概要

该基因是 DAP 激酶相关凋亡诱导蛋白激酶家族的成员,编码具有蛋白激酶结构域的自磷酸化核蛋白。该蛋白具有诱导细胞凋亡的活性。[RefSeq 提供,2008 年 7 月]

This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008]

STK17A 基因产物(1)

mRNA Protein Name
NM_004760.3 NP_004751.2 serine/threonine-protein kinase 17A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
9786912 GOA
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
9786912 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular signal transduction IDA
IDA: 通过直接分析推断
9786912 GOA
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
21489989 GOA
involved in positive regulation of fibroblast apoptotic process IMP
IMP: 通过突变表型推断
9786912 GOA
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
9786912 GOA
involved in regulation of reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
21489989 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9786912 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

STK17A 蛋白结构

Pkinase

Pkinase: Protein kinase domain (64 - 321)

  • 0
  • 100
  • 200
  • 300
  • 414 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase 17A

DAP kinase-related apoptosis-inducing protein kinase 1