2. Gene
  3. DTD1 - D-aminoacyl-tRNA deacylase 1 Gene

DTD1 - D-aminoacyl-tRNA deacylase 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：D-氨酰-tRNA 脱酰酶 1

种属: Homo sapiens

同用名: DTD; DUEB; DUE-B; HARS2; pqn-68; C20orf88

基因 ID: 92675 | 基因类型: protein coding

关于 DTD1

Cytogenetic location: 20p11.23 Genomic coordinates (GRCh38): 20:18,588,054-18,766,644 (from NCBI)

This gene has 3 transcripts (splice variants), 215 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 7.0), brain (RPKM 6.2) and 25 other tissues.

功能概要

该基因编码的蛋白质在序列上与组氨酰-tRNA 合成酶相似，后者将 D-酪氨酰-tRNA (Tyr) 水解为 D-酪氨酸和游离 tRNA (Tyr) 。编码的蛋白质结合 DNA 解旋元件并在 DNA 复制的启动中发挥作用。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2015 年 12 月]

The protein encoded by this gene is similar in sequence to histidyl-tRNA synthetase, which hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). The encoded protein binds the DNA unwinding element and plays a role in the initiation of DNA replication. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

DTD1 基因产物(2)

mRNA Protein Name
NM_001318043.2 NP_001304972.1 D-aminoacyl-tRNA deacylase 1 isoform 1
NM_080820.6 NP_543010.3 D-aminoacyl-tRNA deacylase 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding EXP
EXP: 通过实验结果推断
17264083 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA duplex unwinding EXP
EXP: 通过实验结果推断
17264083 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DTD1 蛋白结构

Tyr_Deacylase

Tyr_Deacylase: D-Tyr-tRNA(Tyr) deacylase (2 - 146)

  • 0
  • 100
  • 209 a.a.
蛋白主名 其他名称

D-aminoacyl-tRNA deacylase 1

D-tyrosyl-tRNA deacylase 1 homolog

重组 DTD1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70087 DTD1 Protein, Human (HEK293, His) Q8TEA8 (M1-P209) ≥95%

关联疾病

疾病名称 别名
Lipoid Proteinosis Of Urbach And Wiethe

Lipoid Proteinosis

Urbach-Wiethe Disease

Hyalinosis Cutis Et Mucosae

Lipid Proteinosis

Lipoproteinosis

Urbach Wiethe Disease

Lipoglycoproteinosis

Lipoidosis Cutis Et Mucosae

Lipoidproteinosis

Urbach-Wiethe Lipoid Proteinosis

Urbach-Wiethe Syndrome

LIP

Proteinosis Lipoid
Spinocerebellar Ataxia 10

Spinocerebellar Ataxia Type 10

SCA10

Spinocerebellar Ataxia-10

Ataxia, Spinocerebellar, Type 10
Ornithosis

Psittacosis

Chlamydial Pneumonia

Chlamydia Psittaci Infection

Chlamydia Psittaci
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04031 DTD1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus DTD1 VGNC VGNC:28228
Felis catus DTD1 VGNC VGNC:80088
Macaca mulatta DTD1 VGNC VGNC:84730
Canis familiaris DTD1 VGNC VGNC:103672
Mus musculus DTD1 MGD MGI:1913294
Rattus norvegicus DTD1 RGD RGD:1311821
Others DTD1 NCBI
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