PPP1R14A - protein phosphatase 1 regulatory inhibitor subunit 14A Gene

中文名称：蛋白磷酸酶 1 调节抑制因子亚基 14A

种属: Homo sapiens

同用名: CPI17; CPI-17; PPP1INL

基因 ID: 94274 | 基因类型: protein coding

关于 PPP1R14A

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:38,251,237-38,256,374 (from NCBI)

This gene has 5 transcripts (splice variants), 217 orthologues and 3 paralogues. Broad expression in fat (RPKM 20.4), spleen (RPKM 15.6) and 20 other tissues.

功能概要

该基因编码的蛋白质属于蛋白磷酸酶 1 (PP1) 抑制剂家族。该蛋白是平滑肌肌球蛋白磷酸酶的抑制剂，磷酸化后具有更高的抑制活性。肌球蛋白磷酸酶的抑制导致肌球蛋白磷酸化增加和平滑肌收缩增强。已经注意到该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2011 年 9 月]

The protein encoded by this gene belongs to the protein Phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin Phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin Phosphatase leads to increased Myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]

PPP1R14A 基因产物(2)

mRNA	Protein	Name
NM_001243947.2	NP_001230876.1	protein phosphatase 1 regulatory subunit 14A isoform 2
NM_033256.3	NP_150281.1	protein phosphatase 1 regulatory subunit 14A isoform 1

PPP1R14A 蛋白结构

PP1_inhibitor

0
100
147 a.a.

蛋白主名

其他名称

protein phosphatase 1 regulatory subunit 14A

17 kDa PKC-potentiated inhibitory protein of PP1

重组 PPP1R14A 蛋白

目录号	产品名	蛋白编号	纯度
HY-P71229	PPP1R14A Protein, Human (His)	Q96A00-1 (M1-P147)	≥95%

关联疾病

疾病名称

别名

Israeli Tick Typhus

Israeli Spotted Fever

Japanese Spotted Fever

Oriental Spotted Fever

Rickettsia Japonica Spotted Fever

Indian Tick Typhus

Melon Allergy

Cucumis Melo Fruit Allergy

Epidemic Typhus

Typhus	Typhus Fever
Epidemic Louse-Borne Typhus Fever Due To Rickettsia Prowazekii	Murine Typhus
Classical Typhus	Endemic Flea-Borne Typhus
Endemic Typhus Fever	Epidemic Louse-Borne Typhus
Famine Fever	Flea-Borne Typhus
Jail Fever	Louse-Borne Typhus
Mexican Typhus	Shop Typhus
Urban Typhus	Brill-Zinsser Disease
Endemic Typhus	Sylvatic Typhus
Epidemic Typhus	European Typhus
Exanthematic Typhus Fever	Exanthematous Typhus
Flea Typhus	Flea-Borne Rickettsiosis
Hospital Fever	Louse-Borne [Epidemic] Typhus
Louse-Borne Rickettsiosis	Moscow Typhus
Murine [Endemic] Typhus	Petechial Fever
Prison Fever	Rat Flea Typhus
Ship Fever	Typhus Exanthematique
Typhus, Endemic Flea-Borne	Typhus, Epidemic Louse-Borne
Typhus Group Rickettsial Disease	Relapsing Fever
Typhus Fever Nos	Typhus Nos
Epidemic Typhus Fever	Louse-Borne Typhus Fever
Classical Typhus Fever	Louse-Borne Tabardillo
Epidemic Typhus Fever Due To Rickettsia Prowazekii	Endemic Murine Typhus
Flea-Borne Typhus Fever	Murine Endemic Flea Typhus
Rat Typhus	Typhus Due To Rickettsia Typhi
Flea-Borne Tabardillo	Rickettsia Typhi Rickettsiosis
Mexican Fever	Murine Flea-Borne Typhus
Mooser Bodies	Tsutsugamushi Fever
Kedani Fever	Mite-Borne Typhus
Mite-Borne Typhus Due To Rickettsia Tsutsugamushi	Scrub Typhus
Tsutsugamushi	Tsutsugamushi Disease
Scrub Mite-Borne Typhus	Sumatran Mite Fever
Japanese River Fever	Kedani Typhus
Rickettsia Tsutsugamushi Rickettsiosis	Sumatran Mite Typhus
Tropical Typhus	Japanese Typhus

Cat-Scratch Disease

Cat Scratch Disease	Benign Lymphoreticulosis
Cat Scratch Fever	Debre'S Syndrome
Bartonellosis Due To Bartonella Henselae Infection	Debre-Mollaret Syndrome
Foshay-Mollaret Cat Scratch Fever	Oroya Fever
Cat-Scratch Fever	Benign Inoculation Lymphoreticulosis
Catscratch Disease Or Fever	Csd - [Cat Scratch Disease]
Nonbacterial Regional Lymphadenitis	Rochalimaea Henselae Infection

Pediculus Humanus Corporis Infestation

Body Louse Infestation	Pediculus Corporis
Pediculus Humanus Infestation

Ocular Hyperemia

Hyperemia Eye

Hyperemia Of Conjunctiva

African Tick-Bite Fever

Rickettsia Africae Spotted Fever	South African Tick-Bite Fever
African Tick Bite Fever

Bartonellosis

Bartonella Infections	Bartonella Infectious Disease
Bartonelliasis	Rochalimaea Infection
Bartonellosis, Unspecified

Rocky Mountain Spotted Fever

Brazillian Spotted	Choix
Exanthematic Typhus Of Sao Paulo	Fiebre Maculosa
Fiebre Manchada	Sao Paulo Typhus
So Paulo Fever	Tick Typhus
Tobia Fever	Rmsf
Typhus, Tick

Endemic Typhus

Murine Typhus	Cat Flea Rickettsiosis
Fleaborne Typhus	Rat-Flea Typhus
Rickettsia Felis Spotted Fever	Shop Typhus
Toulon Typhus	Urban Typhus
Urban Typhus Of Malaya	Flea-Borne Typhus
Endemic Flea-Borne Typhus

Ophthalmia Nodosa

Spotted Fever

Spotted Fevers	Spotted Fever Group Rickettsial Disease
Tick-Borne Rickettsioses	Tick-Borne Typhus Nos
Rocky Mountain Spotted Fever	Sao Paulo Fever
Sao Paulo Typhus	Lone Star Spotted Fever
Colombian Spotted Fever	American Spotted Fever
Tick Typhus Due To Rickettsia Rickettsii	Rocky Mountain Tick Fever
Boutonneuse Fever	Mediterranean Tick Fever
Fièvre Boutonneuse	Mediterranean Spotted Fever
Tick Typhus Due To Rickettsia Conorii	African Tick Typhus
Indian Tick Typhus	Kenya Tick Typhus
North Asian Tick Fever	Siberian Tick Typhus
Tick Typhus Due To Rickettsia Siberica	North Asian Spotted Fever
Queensland Tick Typhus	Queensland Fever

Bacillary Angiomatosis

Angiomatosis, Bacillary

Dracunculiasis

Guinea Worm Disease	Dracontiasis
Dracunculosis	Infection By Dracunculus Medinensis
Gwd	Guinea Worm Infection
Parasitic Infection Caused By Dracunculus Medinensis	Medina Worm Disease
Medinensis	Medina Worm Infestation
Dracunculus Medinensis Infestation	Guinea Worm Infestation

Boutonneuse Fever

Mediterranean Spotted Fever	African Tick Typhus
Boutonneuse Disease	Conor And Bruch'S Disease
Kenya Fever	Kenya Tick Typhus
Kenyan Tick Typhus	Marseilles Fever
Mediterranean Tick Fever	Rickettsia Conorii Spotted Fever
South African Tick-Bite Fever	African Tick Bite Fever

Cholinergic Urticaria

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS10983	PPP1R14A Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	PPP1R14A	VGNC	VGNC:53753
Mus musculus	PPP1R14A	MGD	MGI:1931139
Rattus norvegicus	PPP1R14A	RGD	RGD:620536
Macaca mulatta	PPP1R14A	VGNC	VGNC:76255
Bos taurus	PPP1R14A	VGNC	VGNC:33226
Others	PPP1R14A	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

PPP1R14A - protein phosphatase 1 regulatory inhibitor subunit 14A Gene

关于 PPP1R14A

功能概要

PPP1R14A 基因产物(2)

PPP1R14A 蛋白结构

重组 PPP1R14A 蛋白

关联疾病

直系同源

热门区域

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PPP1R14A - protein phosphatase 1 regulatory inhibitor subunit 14A Gene

关于 PPP1R14A

功能概要

PPP1R14A 基因产物(2)

PPP1R14A 蛋白结构

重组 PPP1R14A 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z