2. Gene
  3. SH3BP5 - SH3 domain binding protein 5 Gene

SH3BP5 - SH3 domain binding protein 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：SH3 结构域结合蛋白 5

种属: Homo sapiens

同用名: SAB; SH3BP-5

基因 ID: 9467 | 基因类型: protein coding

关于 SH3BP5

Cytogenetic location: 3p25.1 Genomic coordinates (GRCh38): 3:15,254,353-15,341,380 (from NCBI)

This gene has 9 transcripts (splice variants), 276 orthologues and 1 paralogue. Ubiquitous expression in adrenal (RPKM 64.1), fat (RPKM 35.1) and 24 other tissues.

功能概要

启用胍基核苷酸交换因子活性和蛋白激酶抑制剂活性。作用于细胞内信号转导的上游或内部。位于细胞质囊泡膜和核体中。 [由基因组资源联盟提供，2022 年 4 月]

Enables guanyl-nucleotide exchange factor activity and protein kinase inhibitor activity. Acts upstream of or within intracellular signal transduction. Located in cytoplasmic vesicle membrane and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

SH3BP5 基因产物(2)

mRNA Protein Name
NM_001018009.4 NP_001018009.2 SH3 domain-binding protein 5 isoform b
NM_004844.5 NP_004835.2 SH3 domain-binding protein 5 isoform a

SH3BP5 蛋白结构

SH3BP5

SH3BP5: SH3 domain-binding protein 5 (SH3BP5) (37 - 270)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 455 a.a.
蛋白主名 其他名称

SH3 domain-binding protein 5

SH3 domain-binding protein that preferentially associates with BTK

SH3BP5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SH3BP5 O60239 NAP1L2 Homo sapiens Q9ULW6
Validated Y2H
32296183
种属内
SH3BP5 O60239 NAP1L2 Homo sapiens Q9ULW6
Y2H Array
32296183
种属内
SH3BP5 O60239 NAP1L2 Homo sapiens Q9ULW6
Y2H Prey Pooling
32296183
种属内
SH3BP5 O60239 BTK Homo sapiens Q06187
Pull Down
9571151
种属内
SH3BP5 O60239 IFT20 Homo sapiens Q8IY31-3
Validated Y2H
32296183
种属内
SH3BP5 O60239 IFT20 Homo sapiens Q8IY31-3
Y2H Array
32296183
种属内
SH3BP5 O60239 IFT20 Homo sapiens Q8IY31-3
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Agammaglobulinemia, X-Linked

X-Linked Agammaglobulinemia

XLA

Bruton Type Agammaglobulinemia

Bruton'S Agammaglobulinemia

Bruton-Type Agammaglobulinemia

Agmx1

Imd1

Agammaglobulinemia, X-Linked 1

Btk-Deficiency

Agammaglobulinemia

Hypogammaglobulinemia

Agammaglobulinemia, X-Linked, Type 1

Immunodeficiency 1

Bruton Agammaglobulinemia Tyrosine Kinase Deficiency

Bruton Disease

Bruton'S Agammaglobulinaemia

Bruton'S Sex-Linked Agammaglobulinemia

Bruton'S Type Agammaglobulinemia

Btk Deficiency

Agammaglobulinemia, Btk

Agammaglobulinemia, Bruton Tyrosine Kinase

Congenital Agammaglobulinemia

Immunodeficiency Type 1

X-Linked Agammaglobulinemia Type 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12833 SH3BP5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SH3BP5 MGD MGI:1344391
Felis catus SH3BP5 VGNC VGNC:65103
Rattus norvegicus SH3BP5 RGD RGD:620220
Bos taurus SH3BP5 VGNC VGNC:34568
Canis familiaris SH3BP5 VGNC VGNC:46120
Macaca mulatta SH3BP5 VGNC VGNC:77203
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