CHST3 - carbohydrate sulfotransferase 3 Gene

中文名称：碳水化合物磺基转移酶 3

种属: Homo sapiens

同用名: HSD; C6ST; C6ST1

基因 ID: 9469 | 基因类型: protein coding

关于 CHST3

Cytogenetic location: 10q22.1 Genomic coordinates (GRCh38): 10:71,964,395-72,013,558 (from NCBI)

This gene has 1 transcript (splice variant), 247 orthologues, 6 paralogues and is associated with 4 phenotypes. Broad expression in testis (RPKM 10.9), ovary (RPKM 8.0) and 21 other tissues.

功能概要

该基因编码一种催化软骨素硫酸化的酶，软骨素是一种在细胞外基质和大多数细胞中发现的蛋白多糖，参与细胞迁移和分化。该基因的突变与脊椎骨骺发育不良和肱脊柱发育不良有关。[RefSeq 提供，2009 年 3 月]

This gene encodes an Enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis. [provided by RefSeq, Mar 2009]

CHST3 基因产物(1)

mRNA	Protein	Name
NM_004273.5	NP_004264.2	carbohydrate sulfotransferase 3

基因本体论

分子功能
生物过程

分子功能 GO 注释	逻辑证据	参考文献	来源
enables chondroitin 6-sulfotransferase activity	IDA IDA: 通过直接分析推断	9883891	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in chondroitin sulfate biosynthetic process	IDA IDA: 通过直接分析推断	9883891	GOA
involved in chondroitin sulfate biosynthetic process	IMP IMP: 通过突变表型推断	15215498	GOA
involved in sulfur compound metabolic process	IDA IDA: 通过直接分析推断	9883891	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CHST3 蛋白结构

Sulfotransfer_1

0
100
200
300
400
479 a.a.

蛋白主名

其他名称

carbohydrate sulfotransferase 3

C6ST-1

关联疾病

疾病名称

别名

Spondyloepiphyseal Dysplasia With Congenital Joint Dislocations

Spondyloepiphyseal Dysplasia	Chst3-Related Skeletal Dysplasia
Humerospinal Dysostosis	Spondyloepiphyseal Dysplasia, Omani Type
Chondrodysplasia With Multiple Dislocations	SEDCJD
Hsd	Cdmd
Humero-Spinal Dysostosis	Kozlowski Celermajer Tink Syndrome
Chondrodysplasia With Congenital Joint Dislocations, Chst3 Type	Larsen Syndrome, Recessive Type
Humero-Spinal Dysostosis With Congenital Heart Disease	Omani Type
Sed	Chst3 Deficiency
Chst3-Related Dysplasia	Recessive Larsen Syndrome
Autosomal Recessive Larsen Syndrome	Sed With Luxations, Chst3 Type
Sed, Omani Type	Sdcd, Chst3 Type
Spondyloepiphyseal Dysplasia With Congenital Joint Dyslocations, Chst3 Type	Sed Omani Type
Spondyloepiphyseal Dysplasia Omani Type	Larsen Syndrome, Autosomal Recessive
Mucopolysaccharidosis Iv	Spondyloepiphyseal Dysplasia, Congenita

Larsen Syndrome

LRS	Larsen Syndrome, Dominant Type
Dominant Larsen Syndrome	Autosomal Dominant Larsen Syndrome
Larsens Syndrome

Larsen-Like Syndrome B3gat3 Type

Larsen-Like Syndrome, B3gat3 Type	Multiple Joint Dislocations-Short Stature-Craniofacial Dysmorphism-Congenital Heart Defects Syndrome
Multiple Joint Dislocations, Short Stature, And Craniofacial Dysmorphism With Congenital Heart Defects	Joint Dislocations, Multiple, Short Stature, Craniofacial Dysmorphism, Congenital Heart Defects

Congenital Joint Dislocations

Dysostosis

Dysostoses

Desbuquois Dysplasia

Desbuquois Syndrome	Micromelic Dwarfism With Vertebral And Metaphyseal Abnormalities And Advanced Carpotarsal Ossification
Dysplasia, Desbuquois

Clubfoot

Congenital Talipes Equinovarus	Congenital Clubfoot
Congenital Equinovarus	Equinovarus Deformity Of Foot
Club Foot

Ehlers-Danlos Syndrome, Musculocontractural Type, 1

Ehlers-Danlos Syndrome, Musculocontractural Type 1	EDSMC1
Edsmc	Adducted Thumb-Clubfoot Syndrome
Atcs	Dundar Syndrome
Arthrogryposis, Distal, With Peculiar Facies And Hydronephrosis	Ehlers-Danlos Syndrome Musculocontractural Type 1
Adducted Thumb, Clubfoot, And Progressive Joint And Skin Laxity Syndrome	Ehlers-Danlos Syndrome, Type Vib, Formerly
Eds6b, Formerly	Adducted Thumbs-Arthrogryposis Dundar Type
Arthrogryposis Distal With Peculiar Facies And Hydronephrosis	Eds6b Formerly
Ehlers-Danlos Syndrome Type Vib Formerly	Ehlers-Danlos, Musculocontractural Syndrome, Type 1

Temtamy Preaxial Brachydactyly Syndrome

Preaxial Brachydactyly Syndrome, Temtamy Type	TPBS
Intellectual Disability Syndrome With Preaxial Brachydactyly, Hyperphalangism, Deafness And Orodental Anomalies	Preaxial Brachydactyly Syndrome Temtamy Type

Saul-Wilson Syndrome

Microcephalic Osteodysplastic Dysplasia	Microcephalic Osteodysplastic Dysplasia, Saul-Wilson Type
SWILS	Microcephalic Osteodysplastic Dysplasia Saul Wilson Type

Macular Dystrophy, Corneal

Macular Corneal Dystrophy	MCD
Corneal Dystrophy, Macular Type	Groenouw Type Ii Corneal Dystrophy
Fehr Corneal Dystrophy	Macular Dystrophy, Corneal Type 1
Mcdc1	Macular Corneal Dystrophy Type Ii
Macular Corneal Dystrophy, Type Ii	Macular Corneal Dystrophy, Type I
Mcdc1, Formerly	Macular Dystrophy, Corneal, 1
Macular Corneal Dystrophy Type 1	Corneal Dystrophy Groenouw Type Ii
Corneal Dystrophy Macular Type	Macular Corneal Dystrophy Type I
Dystrophy, Macular, Corneal

Brachyolmia

Brachyrachia

Osteochondrodysplasia

Skeletal Dysplasia	Chondrodystrophy
Congenital Anomaly Of Cartilage	Osteochondrodysplasias
Cartilage Development Disorder	Osteochondrodysplasia Syndrome
Dysplasia, Skeletal	Mucopolysaccharidosis Iv

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS02689	CHST3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	CHST3	MGD	MGI:1858224
Felis catus	CHST3	VGNC	VGNC:60890
Rattus norvegicus	CHST3	RGD	RGD:620355
Macaca mulatta	CHST3	VGNC	VGNC:106024
Canis familiaris	CHST3	VGNC	VGNC:39255
Bos taurus	CHST3	VGNC	VGNC:27345
Others	CHST3	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

CHST3 - carbohydrate sulfotransferase 3 Gene

关于 CHST3

功能概要

CHST3 基因产物(1)

CHST3 蛋白结构

关联疾病

直系同源

热门区域

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CHST3 - carbohydrate sulfotransferase 3 Gene

关于 CHST3

功能概要

CHST3 基因产物(1)

CHST3 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z