1. Gene
  2. PGS1 - phosphatidylglycerophosphate synthase 1 Gene

PGS1 - phosphatidylglycerophosphate synthase 1 Gene

中文名称:磷脂酰甘油磷酸合酶 1

种属: Homo sapiens

基因 ID: 9489 | 基因类型: protein coding

关于 PGS1

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:78,378,649-78,424,659 (from NCBI)

This gene has 15 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in bone marrow (RPKM 9.6), appendix (RPKM 8.4) and 25 other tissues.

功能概要

预计可启用 CDP-二酰基甘油-甘油-3-磷酸 3-磷脂酰转移酶活性和钙离子结合活性。预计参与心磷脂生物合成过程和甘油二酯代谢过程。位于内质网。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity and calcium ion binding activity. Predicted to be involved in cardiolipin biosynthetic process and diacylglycerol metabolic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

PGS1 基因产物(1)

mRNA Protein Name
NM_024419.5 NP_077733.3 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial precursor
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in mitochondrion IDA
IDA: 通过直接分析推断
38322995 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PGS1 蛋白结构

PLDc_2

PLDc_2: PLD-like domain (111 - 259)

  • 0
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  • 200
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  • 500
  • 556 a.a.
蛋白主名 其他名称

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial

PGP synthase 1

直系同源

种属 基因名 来源 基因 ID
Felis catus PGS1 VGNC VGNC:64127
Rattus norvegicus PGS1 RGD RGD:1305052
Bos taurus PGS1 VGNC VGNC:32803
Macaca mulatta PGS1 VGNC VGNC:75890
Canis familiaris PGS1 VGNC VGNC:44472
Mus musculus PGS1 MGD MGI:1921701