2. Gene
  3. C2CD5 - C2 calcium dependent domain containing 5 Gene

C2CD5 - C2 calcium dependent domain containing 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 C2 钙依赖域 5

种属: Homo sapiens

同用名: CDP138; KIAA0528

基因 ID: 9847 | 基因类型: protein coding

关于 C2CD5

Cytogenetic location: 12p12.1 Genomic coordinates (GRCh38): 12:22,448,583-22,544,542 (from NCBI)

This gene has 18 transcripts (splice variants) and 204 orthologues. Ubiquitous expression in thyroid (RPKM 12.3), colon (RPKM 12.2) and 25 other tissues.

功能概要

启用钙离子结合活性和钙依赖性磷脂结合活性。参与细胞对胰岛素刺激的反应；细胞内蛋白质跨膜转运；和运输的积极监管。位于多个蜂窝组件中，包括中心粒卫星；细胞质囊泡膜；和荷叶边膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables calcium ion binding activity and calcium-dependent phospholipid binding activity. Involved in cellular response to Insulin stimulus; intracellular protein transmembrane transport; and positive regulation of transport. Located in several cellular components, including centriolar satellite; cytoplasmic vesicle membrane; and ruffle membrane. [provided by Alliance of Genome Resources, Apr 2022]

C2CD5 基因产物(18)

mRNA Protein Name
NM_001286173.2 NP_001273102.1 C2 domain-containing protein 5 isoform c
NM_001286174.3 NP_001273103.1 C2 domain-containing protein 5 isoform a
NM_001286175.2 NP_001273104.1 C2 domain-containing protein 5 isoform b
NM_001286176.2 NP_001273105.1 C2 domain-containing protein 5 isoform a
NM_001286177.2 NP_001273106.1 C2 domain-containing protein 5 isoform d
NM_001385322.1 NP_001372251.1 C2 domain-containing protein 5 isoform f
NM_001385323.1 NP_001372252.1 C2 domain-containing protein 5 isoform g
NM_001385324.1 NP_001372253.1 C2 domain-containing protein 5 isoform h
NM_001385325.1 NP_001372254.1 C2 domain-containing protein 5 isoform i
NM_001385326.1 NP_001372255.1 C2 domain-containing protein 5 isoform j
NM_001385327.1 NP_001372256.1 C2 domain-containing protein 5 isoform k
NM_001385328.1 NP_001372257.1 C2 domain-containing protein 5 isoform l
NM_001385329.1 NP_001372258.1 C2 domain-containing protein 5 isoform m
NM_001385330.1 NP_001372259.1 C2 domain-containing protein 5 isoform n
NM_001385331.1 NP_001372260.1 C2 domain-containing protein 5 isoform o
NM_001385332.1 NP_001372261.1 C2 domain-containing protein 5 isoform p
NM_001385333.1 NP_001372262.1 C2 domain-containing protein 5 isoform q
NM_014802.3 NP_055617.1 C2 domain-containing protein 5 isoform e
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
21907143 GOA
enables calcium-dependent phospholipid binding IDA
IDA: 通过直接分析推断
21907143 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
21907143 GOA
involved in intracellular protein transmembrane transport IMP
IMP: 通过突变表型推断
21907143 GOA
involved in positive regulation of protein targeting to membrane IMP
IMP: 通过突变表型推断
21907143 GOA
involved in positive regulation of vesicle fusion IMP
IMP: 通过突变表型推断
21907143 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell cortex IDA
IDA: 通过直接分析推断
21907143 GOA
located in cytoplasmic vesicle membrane IDA
IDA: 通过直接分析推断
21907143 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
21907143 GOA
located in ruffle membrane IDA
IDA: 通过直接分析推断
21907143 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

C2CD5 蛋白结构

C2

C2: C2 domain (5 - 89)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000 a.a.
蛋白主名 其他名称

C2 domain-containing protein 5

138 kDa C2 domain-containing phosphoprotein

关联疾病

疾病名称 别名
Protoplasmic Astrocytoma

Protoplasmic Astrocytic Tumor

Astrocytoma Protoplasmic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01741 C2CD5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus C2CD5 MGD MGI:1921991
Felis catus C2CD5 VGNC VGNC:60230
Canis familiaris C2CD5 VGNC VGNC:38590
Macaca mulatta C2CD5 VGNC VGNC:70665
Bos taurus C2CD5 VGNC VGNC:26636
Rattus norvegicus C2CD5 RGD RGD:1304592
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