P2RY14 - purinergic receptor P2Y14 Gene

中文名称：嘌呤能受体 P2Y14

种属: Homo sapiens

同用名: P2Y14; BPR105; GPR105

关于 P2RY14

功能概要

该基因的产物属于 G 蛋白偶联受体家族，包含多种受体亚型，对各种腺苷和尿苷核苷酸具有不同的药理选择性。该受体是 UDP-葡萄糖和其他与 G 蛋白偶联的 UDP-糖的 P2Y 嘌呤能受体。它涉及通过参与干细胞区室的调节来扩展 P2Y 受体的已知免疫系统功能，并且它还可能在神经免疫功能中发挥作用。已为该基因鉴定出编码相同蛋白质的两个转录物变体。[RefSeq 提供，2008 年 7 月]

The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and Other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]