2. Neuronal Signaling Membrane Transporter/Ion Channel Metabolic Enzyme/Protease
  3. nAChR Endogenous Metabolite
  4. Glycerophosphoinositol choline

Glycerophosphoinositol choline  (Synonyms: 甘油磷酸肌醇胆碱)

目录号: HY-B1337B
产品使用指南

摩尔计算器

Glycerophosphoinositol choline 是一种必需营养素，可激活 α7 烟碱受体 (alpha7 nicotinic receptors)，具有镇痛、抗炎活性。可影响肝脏疾病、动脉粥样硬化和神经系统疾病等疾病。

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Glycerophosphoinositol choline Chemical Structure

Glycerophosphoinositol choline Chemical Structure

CAS No. : 425642-32-6

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规格 是否有货
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100 mg   询价  
250 mg   询价  

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Glycerophosphoinositol choline 的其他形式现货产品:

Customer Review

Other Forms of Glycerophosphoinositol choline:

Glycerophosphoinositol choline 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Glycerophosphoinositol choline is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders[1][2].

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Glycerophosphoinositol choline (0 or 70 μM, 4 days) can effectively mitigate apoptosis and maintain cell viability[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Glycerophosphoinositol choline 相关抗体:

Cell Viability Assay[1]

Cell Line: Rat pheochromocytoma cells PC12
Concentration: 0 or 70 μM
Incubation Time: 4 days
Result: Showed the cell viability of 94% at 70 μM while cell viability of 83% at 0 μM.
Reduced the number of cells with DNA breaks (characteristic of apoptosis) by 8.5% at 70 μM compared to the no treatment group.
体内研究
(In Vivo)

Glycerophosphoinositol choline (s.c., 0.2 and 100 mg/kg/h, 24 or 48 hours) can reduce postoperative injurious reflexes and effectively decreases tumor necrosis factor (TNF) release from macrophages in female C57/Bl6 mice[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Postoperative pain model of female C57/Bl6 mice[2]
Dosage: 0.2 and 100 mg/kg/h
Administration: Subcutaneous injection, 24 or 48 hours
Result: Reduced heat hypersensitivity after surgery with maximal efficacy after 48 h treatment and the ED50 value of choline dose was 1.7 mg/kg/h.
Reduced hypersensitivity to punctate mechanical stimuli 48 hours after infusion in a dose-dependent manner and with the ED50 value of 4.7 mg/kg/h but not 24 hours.
Clinical Trial
分子量

437.38

Formula

C14H32NO12P
CAS 号
中文名称

甘油磷酸肌醇胆碱
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Glycerophosphoinositol choline 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glycerophosphoinositol425642-32-6甘油磷酸肌醇胆碱nAChREndogenous MetaboliteNicotinic acetylcholine receptorscholinealpha7 nicotinic receptoranalgesicanti-inflammatoryInhibitorinhibitorinhibit

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