2. 天然产物
  3. 植物 萜类
  4. 豆科 菊科 倍半萜
  5. 山葛
  6. Gochnatiolide A

Gochnatiolide A 是一种二聚倍半萜烯，可在 Ainsliaea henryi 中发现。Gochnatiolide A 对肾脏、黑色素瘤、卵巢抵抗和神经胶质瘤细胞系具有抗增殖活性。

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Gochnatiolide A Chemical Structure

Gochnatiolide A Chemical Structure

CAS No. : 87606-12-0

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规格 价格 是否有货 数量
1 mg ￥6000
1 - 2 周
5 mg 现货 1 - 2 周
10 mg 现货 1 - 2 周
50 mg   询价  
100 mg   询价  

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Gochnatiolide A 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gochnatiolide A is a dimeric sesquiterpene that can be found in Ainsliaea henryi. Gochnatiolide A exhibits antiproliferative activity against the kidney, melanoma, ovarian-resistant and glioma cell lines[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
C6 IC50
1.2 μM
Compound: 4
Cytotoxicity against rat C6 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
Cytotoxicity against rat C6 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
[PMID: 34496568]
HCCLM3 IC50
> 10 μM
Compound: 4
Cytotoxicity against human HCCLM3 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
Cytotoxicity against human HCCLM3 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
[PMID: 34496568]
HeLa IC50
2.8 μM
Compound: 4
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
[PMID: 34496568]
Huh-7 IC50
2.5 μM
Compound: 4
Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
[PMID: 34496568]
PANC-1 IC50
2.2 μM
Compound: 4
Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
[PMID: 34496568]
体外研究
(In Vitro)

Gochnatiolide A (0.25-250 μg/mL; 48 h) 抑制细胞生长，对 786.0，UACC-62，NCI-ADR/RES，U251，MCF-7，NCI-H460，HT-29，PC-3，OVCAR-3，VERO 和 K562 细胞的 TGI (总生长抑制) 值分别为 0.42，0.49，0.70，1.09，1.69，4.66，5.42，6.63，54.73，13.13 和 114.87 μg/mL[2] 。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Gochnatiolide A 相关抗体:
分子量

502.56

Formula

C30H30O7
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Gochnatiolide A 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gochnatiolide A87606-12-0OthersAinsliaea henryiantiproliferativekidneymelanomaovarian-resistantgliomaInhibitorinhibitorinhibit

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目录号：
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