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GPR17 modulator-1 (Compound 2-046) 是 G 蛋白偶联受体 17 GPR17 的调节剂,在 CHO 中对 hGPR17IC50<10 nM。GPR17 modulator-1 在小鼠中表现出适中的药代动力学特征。GPR17 modulator-1 具有血脑屏障 (BBB) 通透性。

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GPR17 modulator-1 Chemical Structure

GPR17 modulator-1 Chemical Structure

CAS No. : 3039853-91-0

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  • 生物活性

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生物活性

GPR17 modulator-1 (Compound 2-046) is a modulator for G protein-coupled receptor 17 GPR17, with an IC50<10 nM for hGPR17 in CHO. GPR17 modulator-1 exhibits moderate pharmacokinetic characteristics in mice. GPR17 modulator-1 ix blood-brain barrier (BBB) permeable[1].

分子量

436.79

Formula

C15H12ClF3N4O4S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献

GPR17 modulator-1 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
GPR17 modulator-1
目录号:
HY-164311
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