2. Neuronal Signaling PI3K/Akt/mTOR Apoptosis Stem Cell/Wnt
  3. Tau Protein GSK-3 Apoptosis
  4. GSK-3β inhibitor 15

GSK-3β inhibitor 15 (Compound 54) 是一种 GSK-3β 抑制剂 (IC50: 3.4 nM)。GSK-3β inhibitor 15 抑制 Aβ1-42 诱导的 GSK-3β 和 tau 蛋白 磷酸化GSK-3β inhibitor 15 抑制 LPS 诱导的 iNOS 表达。GSK-3β inhibitor 15 对 Aβ1-42 诱导的神经毒性具有神经保护作用。GSK-3β inhibitor 15 可用于阿尔茨海默病 (AD) 的研究。

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GSK-3β inhibitor 15 Chemical Structure

GSK-3β inhibitor 15 Chemical Structure

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GSK-3β inhibitor 15 相关抗体

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GSK-3 GSK-3α GSK-3β

  • 生物活性

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  • 参考文献

生物活性

GSK-3β inhibitor 15 (Compound 54) is a GSK-3β inhibitor (IC50: 3.4 nM). GSK-3β inhibitor 15 inhibits Aβ1-42-induced GSK-3β and tau protein phosphorylation. GSK-3β inhibitor 15 inhibits LPS-induced iNOS expression. GSK-3β inhibitor 15 has neuroprotective effects on Aβ1-42-induced neurotoxicity. GSK-3β inhibitor 15 can be used for research of Alzheimer’s disease (AD)[1].

分子量

352.41

Formula

C17H16N6OS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GSK-3β inhibitor 15 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK-3β inhibitor 15Tau ProteinGSK-3ApoptosisGlycogen synthase kinase-3Glycogen synthase kinase 3iNOSLPStau hyperphosphorylationAβ1-42dyskinesiaAlzheimer’sADastrocytesmicrogliaInhibitorinhibitorinhibit

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