2. Anti-infection
  3. HIV Reverse Transcriptase
  4. GW695634

GW695634 是具有口服活性的 GW678248 的前药。GW695634 在体内经过酰胺水解作用，释放出活性成分 GW678248 从而抑制病毒的复制。GW678248 是一种非核苷类逆转录酶抑制剂 (NNRTi)，对耐 Efavirenz (HY-10572) 和耐 Nevirapine (HY-10570) 的 HIV 和 AIDS 病毒具有有效的抗病毒活性。

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GW695634 Chemical Structure

GW695634 Chemical Structure

CAS No. : 457635-65-3

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GW695634 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GW695634 is an orally active prodrug of GW678248. GW695634 undergoes amidolysis in vivo to release the active ingredient GW678248, thereby inhibiting viral replication. GW678248 is a non-nucleoside reverse transcriptase inhibitor (NNRTi) with potent antiviral activity against Efavirenz (HY-10572)-resistant and Nevirapine (HY-10570)-resistant HIV and AIDS viruses[1].

分子量

574.43

Formula

C26H21Cl2N3O6S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GW695634 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GW695634457635-65-3GW 695634GW-695634HIVReverse TranscriptaseHuman immunodeficiency virusProdrugAIDSAntiviralNNRTiInhibitorinhibitorinhibit

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