2. 点击化学
  3. 叠氮化物
  4. hCAXII-IN-10

hCAXII-IN-10 (Compound 18b) 是人碳酸酐酶异构体 XII (hCAXII) 和组织蛋白酶 B (cathepsin B) 的双重抑制剂，Ki 值为 2.2 nM。hCAXII-IN-10 可以抑制 hCAXII 为肿瘤提供有利于肿瘤生长的 pH 微环境的作用，有望用于肿瘤疾病的研究。

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hCAXII-IN-10 Chemical Structure

hCAXII-IN-10 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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hCAXII-IN-10 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

hCAXII-IN-10 (Compound 18b) is a dual inhibitor of human carbonic anhydrase isoform XII (hCAXII) and cathepsin B, with a Ki value of 2.2 nM. hCAXII-IN-10 can inhibit the role of hCAXII in providing tumors with a pH microenvironment conducive to tumor growth, and is expected to be used in the study of tumor diseases[1].
IC50 & Target

hCAXII, cathepsin B[1].
分子量

437.47

Formula

C20H19N7O3S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

hCAXII-IN-10 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hCAXII-IN-10Othershuman carbonic anhydrasecathepsin Btumor microenvironmentInhibitorinhibitorinhibit

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