2. Others
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  4. HDAC8-IN-13

HDAC8-IN-13是一种组蛋白去乙酰化酶8（HDAC8）抑制剂，具有抗寄生虫活性。HDAC8-IN-13能有效抑制血吸虫的乙酰-L-赖氨酸去乙酰化酶活性，影响寄生虫的感染能力。HDAC8-IN-13能够诱导血吸虫细胞的凋亡并导致其死亡。通过特定的结构基础设计，HDAC8-IN-13展示出对人类HDAC的减少亲和力，从而增强其选择性。

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HDAC8-IN-13 Chemical Structure

HDAC8-IN-13 Chemical Structure

CAS No. : 949792-00-1

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HDAC8-IN-13 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HDAC8-IN-13 is a novel histone deacetylase 8 (HDAC8) inhibitor with antiparasitic activity. HDAC8-IN-13 can effectively inhibit the acetyl-L-lysine deacetylase activity of schistosomes, affecting the parasite's infectivity. HDAC8-IN-13 can induce apoptosis and cause the death of schistosome cells. Through a specific structural basis design, HDAC8-IN-13 exhibits reduced affinity for human HDACs, thereby enhancing its selectivity[1].

分子量

238.26

Formula

C10H10N2O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HDAC8-IN-13 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDAC8-IN-13949792-00-1OthersInhibitorinhibitorinhibit

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目录号：
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