1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. Hemitoxin

Hemitoxin 是一种蝎毒肽,是一种 K+ 通道 (K+ channel) 阻滞剂。Hemitoxin 阻断非洲爪蟾卵母细胞中表达的大鼠 Kv1.1、Kv1.2 和 Kv1.3 通道,IC50 值分别为 13 nM、16 nM 和 2 nM。

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Custom Peptide Synthesis

Hemitoxin Chemical Structure

Hemitoxin Chemical Structure

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规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Hemitoxin, a scorpion-venom peptide, is a K+ channel blocker. Hemitoxin blocks rat Kv1.1, Kv1.2 and Kv1.3 channels expressed in Xenopus oocytes with IC50 values of 13 nM, 16 nM and 2 nM, respectively[1].

分子量

3897.58

Formula

C159H259N49O49S8

Sequence

Ile-Lys-Cys-Thr-Leu-Ser-Lys-Asp-Cys-Tyr-Ser-Pro-Cys-Lys-Lys-Glu-Thr-Gly-Cys-Pro-Arg-Ala-Lys-Cys-Ile-Asn-Arg-Asn-Cys-Lys-Cys-Tyr-Gly-Cys-Ser (Disulfide bridge:Cys3-Cys24;Cys9-Cys29;Cys13-Cys19;Cys31-Cys34)

Sequence Shortening

IKCTLSKDCYSPCKKETGCPRAKCINRNCKCYGCS (Disulfide bridge:Cys3-Cys24;Cys9-Cys29;Cys13-Cys19;Cys31-Cys34)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Hemitoxin
目录号:
HY-P5788
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