1. Anti-infection
  2. HIV
  3. HEPT

HEPT 是一种强效且选择性抗 HIV-1 剂。

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HEPT Chemical Structure

HEPT Chemical Structure

CAS No. : 123027-56-5

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查看 HIV 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HEPT is a potent and selective anti-HIV-1 agent[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CCRF-CEM CC50
> 1 μM
Compound: HEPT
Concentration which reduces the cell viability by 50% (CEM-SS / MT-4)
Concentration which reduces the cell viability by 50% (CEM-SS / MT-4)
[PMID: 9191961]
MT4 CC50
> 200 μg/mL
Compound: HEPT
Concentration required to reduce human MT-4 cell viability by 50%.
Concentration required to reduce human MT-4 cell viability by 50%.
[PMID: 1495006]
MT4 CC50
> 25 μg/mL
Compound: HEPT
Cytotoxicity against human MT4 cells after 5 days by MTT assay
Cytotoxicity against human MT4 cells after 5 days by MTT assay
[PMID: 22652226]
MT4 IC50
> 405.38 μM
Compound: HEPT
Antiviral activity against HIV2 ROD infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 4 days by MTT assay
Antiviral activity against HIV2 ROD infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 4 days by MTT assay
[PMID: 18692274]
MT4 IC50
> 405.8 μM
Compound: 1, HEPT
Antiviral activity against HIV2 ROD in MT4 cells after 4 days by MTT method
Antiviral activity against HIV2 ROD in MT4 cells after 4 days by MTT method
[PMID: 17095124]
MT4 CC50
> 500 μM
Compound: 1
Concentration of compound required to reduce the viability of mock infected MT-4 cells against HIV-1 by 50%
Concentration of compound required to reduce the viability of mock infected MT-4 cells against HIV-1 by 50%
[PMID: 2016729]
MT4 CC50
> 500 μM
Compound: HEPT
Cytotoxic concentration required to reduce the viability of mock-infected MT-4 cells (HIV-1 HTLV-IIIB strain) by 50% was determined on 4th day after virus infection.
Cytotoxic concentration required to reduce the viability of mock-infected MT-4 cells (HIV-1 HTLV-IIIB strain) by 50% was determined on 4th day after virus infection.
[PMID: 1992136]
MT4 CC50
≤ 399 μM
Compound: HEPT
Cytotoxicity against human MT4 cells by MTT assay
Cytotoxicity against human MT4 cells by MTT assay
[PMID: 18692274]
MT4 EC50
3.28 μM
Compound: HEPT
Antiviral activity against HIV1 NL4-3 infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days
Antiviral activity against HIV1 NL4-3 infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days
[PMID: 22652226]
MT4 CC50
405 μM
Compound: HEPT
Cytotoxicity against MT4 cells after 4 days by MTT method
Cytotoxicity against MT4 cells after 4 days by MTT method
[PMID: 17381078]
MT4 CC50
405 μM
Compound: 1, HEPT
Cytotoxicity against MT4 cells after 4 days by MTT method
Cytotoxicity against MT4 cells after 4 days by MTT method
[PMID: 17095124]
MT4 CC50
405 μM
Compound: HEPT
Cytotoxic concentration that reduces the MT-4 cell viability by 50%
Cytotoxic concentration that reduces the MT-4 cell viability by 50%
[PMID: 15149669]
MT4 IC50
5.06 μM
Compound: HEPT
Antiviral activity against HIV1 3B infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 4 days by MTT assay
Antiviral activity against HIV1 3B infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 4 days by MTT assay
[PMID: 18692274]
MT4 IC50
5.06 μM
Compound: HEPT
Antiviral activity against wild type HIV1 3B in MT4 cells after 4 days by MTT method
Antiviral activity against wild type HIV1 3B in MT4 cells after 4 days by MTT method
[PMID: 17381078]
MT4 IC50
5.06 μM
Compound: 1, HEPT
Antiviral activity against HIV1 3B in MT4 cells after 4 days by MTT method
Antiviral activity against HIV1 3B in MT4 cells after 4 days by MTT method
[PMID: 17095124]
MT4 IC50
5.06 μM
Compound: HEPT
Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cells
Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cells
[PMID: 15149669]
MT4 CC50
740 μM
Compound: 1
Cytotoxic concentration required to reduce viability of mock-infected MT-4 cells by 50%
Cytotoxic concentration required to reduce viability of mock-infected MT-4 cells by 50%
10.1016/S0960-894X(00)80042-6
MT4 CC50
740 μM
Compound: HEPT
Cytotoxic concentration required to reduce the viability of mock-infected MT-4 cells by 50%
Cytotoxic concentration required to reduce the viability of mock-infected MT-4 cells by 50%
[PMID: 7636846]
MT4 CC50
740 μM
Compound: 5e
Cytotoxic concentration of compound required to reduce the viability of mock-infected MT-4 cells by 50%
Cytotoxic concentration of compound required to reduce the viability of mock-infected MT-4 cells by 50%
[PMID: 2479745]
MT4 CC50
740 μM
Compound: HEPT
Cytotoxic concentration required to reduce the viability of mock-infected MT-4 cells by 50%
Cytotoxic concentration required to reduce the viability of mock-infected MT-4 cells by 50%
[PMID: 1992136]
MT4 CC50
740 μM
Compound: HEPT
Concentration of compound required to reduce the viability of mock-infected HIV-2 (LAV-2ROD)/MT-4 cells by 50%
Concentration of compound required to reduce the viability of mock-infected HIV-2 (LAV-2ROD)/MT-4 cells by 50%
[PMID: 1732552]
MT4 CC50
743 μM
Compound: HEPT
Concentration required to reduce the viability of mock-infected MT-4 cells by 50%.
Concentration required to reduce the viability of mock-infected MT-4 cells by 50%.
[PMID: 1732552]
分子量

308.35

Formula

C14H16N2O4S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

HEPT 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HEPT
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HY-10892
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