2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Hexocyclium methylsulfate

Hexocyclium methylsulfate 是一种 mAChR 拮抗剂，对于 M1、M2、M3 和 M4 亚型的 pKi 值分别为 8.9, 7.7, 8.4, 8.8。Hexocyclium methylsulfate 具有研究十二指肠溃疡和肠易激综合征的潜力。

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Hexocyclium methylsulfate Chemical Structure

Hexocyclium methylsulfate Chemical Structure

CAS No. : 115-63-9

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Hexocyclium methylsulfate 相关抗体

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查看 mAChR 亚型特异性产品:

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mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

  • 生物活性

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  • 参考文献

生物活性

Hexocyclium methylsulfate is a potent mAChR antagonist with pKi values of 8.9, 7.7, 8.4, 8.8 for M1, M2, M3, and M4 subtype, respectively. Hexocyclium methylsulfate has the potential for the research of duodenal ulcer and irritable bowel syndrome[1][2].

IC50 & Target[2]

mAChR1

8.9 (pKi)

mAChR2

7.7 (pKi)

mAChR3

8.4 (pKi)

mAChR4

8.8 (pKi)

分子量

428.59

Formula

C21H36N2O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Hexocyclium methylsulfate 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hexocyclium115-63-9mAChRMuscarinic acetylcholine receptoranticholinergicduodenal ulcerirritable bowel syndromeInhibitorinhibitorinhibit

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产品名称：
Hexocyclium methylsulfate
目录号：
HY-108171A
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