1. Anti-infection
  2. HIV
  3. HIV-1 inhibitor-29

HIV-1 inhibitor-29 (compound 14d2) 是一种有效的 HIV-1 抑制剂,对 HIV-1 IIIB 的 EC50 为 2.18 μM。HIV-1 inhibitor-29 对 F227L/V106A 株具有较高的抗耐药性 (EC50 = 0.974 μM),在 MT-4 细胞中表现出较低的细胞毒性 (CC50 = 211 μM)。HIV-1 inhibitor-29 可用于艾滋病的研究。

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HIV-1 inhibitor-29 Chemical Structure

HIV-1 inhibitor-29 Chemical Structure

CAS No. : 2642217-95-4

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生物活性

HIV-1 inhibitor-29 (compound 14d2) is a potent HIV-1 inhibitor with an EC50 of 2.18 μM for HIV-1 IIIB. HIV-1 inhibitor-29 has high anti-resistance profile toward F227L/V106A strain (EC50 = 0.974 μM), and exhibits low cytotoxicity in MT-4 cells (CC50 = 211 μM). HIV-1 inhibitor-29 can be used for researching AIDS[1].

IC50 & Target[1]

HIV (IIIB)

2.18 μM (EC50)

HIV-1 (F227L/V106A)

0.974 μM (EC50)

分子量

560.64

Formula

C30H36N6O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

HIV-1 inhibitor-29 相关分类

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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
HIV-1 inhibitor-29
目录号:
HY-146353
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