2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. Hongotoxin-1

Hongotoxin-1 是从蝎子 Centruroideslimbatus 的毒液中分离出来的，是钾通道 (potassium channel) 的抑制剂，Kv1.1、Kv1.2、Kv1.3 和 Kv1.6 的 IC50 值分为 31 pM, 170 pM, 86 pM 和 6000 pM。

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Custom Peptide Synthesis

Hongotoxin-1 Chemical Structure

Hongotoxin-1 Chemical Structure

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

Hongotoxin-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Hongotoxin-1, isolated from venom of Centruroides limbatus, is the inhibitor of potassium channel, with IC50 for? Kv1.1, Kv1.2, Kv1.3, and Kv1.6 of 31 pM, 170 pM, 86 pM,and 6000 pM, respectively[1].

IC50 & Target

Kv1.1

31 pM (IC50)

Kv1.2

170 pM (IC50)

Kv1.3

86 pM (IC50)

Kv1.6

6000 pM (IC50)

分子量

4226.13

Formula

C181H299N53O49S7
Sequence

Thr-Val-Ile-Asp-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Ile-Arg-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His (Disulfide bridge:Cys3-Cys17;Cys10-Cys21;Cys16-Cys32)
Sequence Shortening

TVIDVKCTSPKQCLPPCKAQFGIRAGAKCMNGKCKCYPH (Disulfide bridge:Cys3-Cys17;Cys10-Cys21;Cys16-Cys32)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Hongotoxin-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hongotoxin-1Hongotoxin1Hongotoxin 1Potassium ChannelKcsAPotassium Channel InhibitorInhibitorinhibitorinhibit

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产品名称：
Hongotoxin-1
目录号：
HY-P3014
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