1. PROTAC
  2. PROTAC Linkers
  3. Hydroxy-PEG4-methyl acetate

Hydroxy-PEG4-methyl acetate 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

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Hydroxy-PEG4-methyl acetate Chemical Structure

Hydroxy-PEG4-methyl acetate Chemical Structure

CAS No. : 77303-64-1

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25 mg ¥880
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50 mg ¥1400
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100 mg ¥2200
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查看 PROTAC Linkers 亚型特异性产品:

  • 生物活性

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生物活性

Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

266.29

Formula

C11H22O7

CAS 号
性状

液体(密度:1.125 g/cm3

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Hydroxy-PEG4-methyl acetate 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Hydroxy-PEG4-methyl acetate
目录号:
HY-138421
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