2. Metabolic Enzyme/Protease
  3. Indoleamine 2,3-Dioxygenase (IDO)
  4. IDO1-IN-20

HY-146215是一种催化色氨酸氧化代谢的酶，能在肿瘤微环境中对肿瘤进行免疫抑制。

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IDO1-IN-20 Chemical Structure

IDO1-IN-20 Chemical Structure

CAS No. : 2415246-15-8

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规格 是否有货
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IDO1-IN-20 相关抗体

Top Publications Citing Use of Products

查看 Indoleamine 2,3-Dioxygenase (IDO) 亚型特异性产品:

查看所有亚型
IDO1 IDO2 IDO

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Hy-146215 is an enzyme that catalyzes the oxidative metabolism of tryptophan. It can immunosuppress tumors in the tumor microenvironment.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK-293T EC50
69 nM
Compound: 81
Antiproliferative activity against human HEK293T cells assessed as inhibition of cell proliferation by MTT assay
Antiproliferative activity against human HEK293T cells assessed as inhibition of cell proliferation by MTT assay
[PMID: 33569941]
分子量

492.32

Formula

C15H19BrFN7O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

IDO1-IN-20 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IDO1-IN-202415246-15-8Indoleamine 2,3-Dioxygenase (IDO)Inhibitorinhibitorinhibit

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目录号：
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