2. Anti-infection
  3. Influenza Virus
  4. Influenza virus-IN-3

Influenza virus-IN-3 (compound 9) 是一种有效的选择性流感病毒抑制剂，H5N1、H5N2、H5N6、H5N8 的 IC50s 分别为 0.88、0.10、5.5、0.51 µM。Influenza virus-IN-3 显示出抗病毒和 NA (神经氨酸酶) 抑制活性。Influenza virus-IN-3 具有低细胞毒性，CC50 >200 µM。

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Influenza virus-IN-3 Chemical Structure

Influenza virus-IN-3 Chemical Structure

CAS No. : 2412451-16-0

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Influenza virus-IN-3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Influenza virus-IN-3 (compound 9) is a potent and selective influenza virus inhibitor with IC50s of 0.88, 0.10, 5.5, 0.51 µM for H5N1, H5N2, H5N6, H5N8, respectively. Influenza virus-IN-3 shows antiviral and NA (neuraminidase enzyme)-inhibitory activity. Influenza virus-IN-3 shows low cytotoxicity with an CC50 of >200 µM[1].

IC50 & Target

IC50: 0.88 µM (H5N1); 0.10 µM (H5N2); 5.5 µM (H5N6); 0.51 µM (H5N8)[1]
体外研究
(In Vitro)

Influenza virus-IN-3 (compound 9a) shows NA (neuraminidase enzyme)-inhibitory activity with IC50s of 118.17, 1442.6, 34543.33, 78.06, 10206, 0.00048, 0.01222 nM for H5N1, H5N2, H5N6, H5N8, H5N1eH274Y, N1 (H1N1pdm09) and N2 (H3N2), respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Influenza virus-IN-3 相关抗体:
分子量

456.60

Formula

C25H32N2O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Influenza virus-IN-3 相关分类

  • 摩尔计算器

  • 稀释计算器

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Influenza virus-IN-32412451-16-0Influenza Virusoseltamivir derivativeslow cytotoxicityneuraminidase enzymeantiviralchicken embryo fibroblast cellsInhibitorinhibitorinhibit

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