2. Anti-infection
  3. Influenza Virus
  4. Influenza virus-IN-7

Influenza virus-IN-7 (Example 16) 是一种具有口服活性的帽依赖性核酸内切酶 (cap-dependent endonuclease) 抑制剂，可用于流感病毒感染性疾病的研究。

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Influenza virus-IN-7 Chemical Structure

Influenza virus-IN-7 Chemical Structure

CAS No. : 2703046-92-6

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Influenza virus-IN-7 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Influenza virus-IN-7 (Example 16) is an orally active cap-dependent endonuclease inhibitor that can be used for the research of influenza viral infectious diseases[1].

IC50 & Target

IC50: Cap-dependent endonuclease[1]
体外研究
(In Vitro)

Influenza virus-IN-7 (Example 16) 在 MDCK 细胞中显示出对流感 A/Weiss/43(H1N1) 病毒的抗病毒活性，EC50 为 <5 nM (CC50 >1000 nM)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Influenza virus-IN-7 相关抗体:
体内研究
(In Vivo)

Influenza virus-IN-7 (Example 16; 5 mg/kg; i.g.; twice daily for 5 days) 可提高 WSN/33 (H1N1) 感染小鼠模型的存活率[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: WSN/33 (H1N1) infection mouse model[1]
Dosage: 5 mg/kg
Administration: Intragastric administration, twice daily for 5 days
Result: Significantly improved the survival rate.
分子量

612.60

Formula

C29H26F2N4O7S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Influenza virus-IN-7 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Influenza virus-IN-72703046-92-6Influenza Virusinfluenza A/Weiss/43H1N1MDCKWSN/33Inhibitorinhibitorinhibit

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