1. Neuronal Signaling
  2. Transthyretin (TTR)
  3. Inotersen

Inotersen  (Synonyms: GSK-2998728; ISIS-420915)

目录号: HY-112974
产品使用指南

Inotersen 是一种反义寡核苷酸,可抑制肝脏转甲状腺素蛋白 transthyretin (TTR) 的产生。

该游离形式化合物不稳定,推荐具有相同生物学活性的稳定盐形式 Inotersen sodium

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DNA, d(P-thio)([2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]rG-G-T-T-A-m5C-A-T-G-A-A-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rC)

Inotersen Chemical Structure

CAS No. : 1492984-65-2

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Inotersen 的其他形式现货产品:

Customer Review

Other Forms of Inotersen:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Inotersen is an antisense oligonucleotide that inhibits hepatic production of transthyretin (TTR).

Clinical Trial
分子量

7183.08

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Inotersen
目录号:
HY-112974
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