1. JAK/STAT Signaling Stem Cell/Wnt
  2. STAT
  3. inS3-54-A26

inS3-54-A26 是一种 STAT3 抑制剂。inS3-54-A26 对非癌性肺成纤维细胞具有毒性 IC50 为 4.0 μM。

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inS3-54-A26 Chemical Structure

inS3-54-A26 Chemical Structure

CAS No. : 328998-77-2

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生物活性

inS3-54-A26 is a STAT3 inhibitor. inS3-54-A26 has a toxic IC50 of 4.0 μM for non-cancerous lung fibroblasts[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
NCI-H1299 IC50
3.4 μM
Compound: A26
Cytotoxicity against human H1299 cells assessed as inhibition of cell survival after 72 hrs by SRB method
Cytotoxicity against human H1299 cells assessed as inhibition of cell survival after 72 hrs by SRB method
[PMID: 30145375]
分子量

414.88

Formula

C25H19ClN2O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
inS3-54-A26
目录号:
HY-118081
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