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Isaxonine  (Synonyms: 伊沙索宁)

目录号: HY-W129456 纯度: 98.62%
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Isaxonine 作为双层表面 pH 的调节剂。Isaxonine 可加快周围神经再生速度,刺激轴突发芽,促进运动和感觉功能恢复。Isaxonine 是一种神经营养剂。

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Isaxonine Chemical Structure

Isaxonine Chemical Structure

CAS No. : 4214-72-6

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5 mg ¥400
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10 mg ¥560
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25 mg ¥960
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Isaxonine acts as a modifier of the surface pH of the bilayer[1]. Isaxonine accelerates the rate of peripheral nerve regeneration, stimulate axonal sprouting and promote motor and sensory function recovery[2]. Isaxonine is a neurotrophic agent[3].

体外研究
(In Vitro)

Isaxonine has a favourable effect on nerve regeneration. After 8 weeks small type grouping is seen in rats receiving solvent only and large type grouping in rats treated with intraperitoneal Isaxonine. After 10 weeks a checkerboard pattern of the fibre types is observed in the muscles of animals receiving solvent only but fibre type grouping was present in those treated with Isaxonine. Isaxonine prevents synaptic remodelling by suppression of the redundant nerve endings from additional axons, which have regenerated more slowly, in making contact with motor endplates[4].
Isaxonine phosphate induces acute hepatitis which in most cases is reversible after withdrawal of the compound[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

137.18

Formula

C7H11N3

CAS 号
性状

液体(密度:1.065 g/cm3

颜色

Colorless to light yellow

中文名称

伊沙索宁

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶解性数据
细胞实验: 

DMSO 中的溶解度 : 100 mg/mL (728.97 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 7.2897 mL 36.4485 mL 72.8969 mL
5 mM 1.4579 mL 7.2897 mL 14.5794 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.54%

参考文献

Isaxonine 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.2897 mL 36.4485 mL 72.8969 mL 182.2423 mL
5 mM 1.4579 mL 7.2897 mL 14.5794 mL 36.4485 mL
10 mM 0.7290 mL 3.6448 mL 7.2897 mL 18.2242 mL
15 mM 0.4860 mL 2.4299 mL 4.8598 mL 12.1495 mL
20 mM 0.3645 mL 1.8224 mL 3.6448 mL 9.1121 mL
25 mM 0.2916 mL 1.4579 mL 2.9159 mL 7.2897 mL
30 mM 0.2430 mL 1.2149 mL 2.4299 mL 6.0747 mL
40 mM 0.1822 mL 0.9112 mL 1.8224 mL 4.5561 mL
50 mM 0.1458 mL 0.7290 mL 1.4579 mL 3.6448 mL
60 mM 0.1215 mL 0.6075 mL 1.2149 mL 3.0374 mL
80 mM 0.0911 mL 0.4556 mL 0.9112 mL 2.2780 mL
100 mM 0.0729 mL 0.3645 mL 0.7290 mL 1.8224 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Isaxonine
目录号:
HY-W129456
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