1. GPCR/G Protein
  2. GHSR
  3. K-(D-1-Nal)-FwLL-NH2 TFA

K-(D-1-Nal)-FwLL-NH2 TFA 是一种高亲和力、强效的 ghrelin 受体反向激动剂(在 COS7 和 HEK293T 细胞中 K 值分别为 4.9 和 31 nM)。K-(D-1-Nal)-FwLL-NH2 TFA 阻断 ghrelin 受体介导的 Gq 和 G13 依赖性信号通路。

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Custom Peptide Synthesis

K-(D-1-Nal)-FwLL-NH2 TFA Chemical Structure

K-(D-1-Nal)-FwLL-NH2 TFA Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

生物活性

K-(D-1-Nal)-FwLL-NH2 TFA is a high affinity and potent ghrelin receptor inverse agonist (Ki values are 4.9 and 31 nM in COS7 and HEK293T cells, respectively). K-(D-1-Nal)-FwLL-NH2 blocks ghrelin receptor-mediated Gq- and G13-dependent signaling pathways.

分子量

1016.16

Formula

C53H68F3N9O8

Sequence

Lys-{Nal}-Phe-Trp-Leu-Leu-NH2

Sequence Shortening

K{Nal}FWLL-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
K-(D-1-Nal)-FwLL-NH2 TFA
目录号:
HY-P1432A
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