2. Cytoskeleton
  3. Integrin
  4. K34c

K34c 是一种有效的、选择性 α5β1 integrin 拮抗剂。 K34c 可用于胶质母细胞瘤研究。

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K34c Chemical Structure

K34c Chemical Structure

CAS No. : 939769-93-4

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规格 价格 是否有货 数量
5 mg ￥9400
3 - 4 周
10 mg   询价  
50 mg   询价  

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K34c 相关抗体

Top Publications Citing Use of Products

查看 Integrin 亚型特异性产品:

查看所有亚型
αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

K34c is a potent and selective α5β1 integrin antagonist. K34c can be used for glioblastoma research[1].

IC50 & Target[1]

α5β1

 

体外研究
(In Vitro)

K34c (20 μM; 24 or 48 h) significantly induces U87MG cells apoptosis in combination with 1 μM Ellipticine (HY-15753)[1].
K34c (20 μM; 48 h) decreases significantly Temozolomide (HY-17364)-induced senescence in cells transfected with control non targeting siRNA without affecting significantly the residual senescence of cells transfected with siRNA specific for p53[1].
K34c (20 μM; 24 h) modulates the p53 pathway.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

K34c 相关抗体:

Apoptosis Analysis[1]

Cell Line: U87MG cells
Concentration: 20 μM
Incubation Time: 24 or 48 h
Result: Induced apoptosis, led to a significant increase in apoptotic cell death measured by the population of sub-G1 cells in combination with 1 μM Ellipticine (HY-15753).

Western Blot Analysis[1]

Cell Line: U87MG cells
Concentration: 20 μM
Incubation Time: 24 h
Result: Decreased Ellipticine (HY-15753)- and Temozolomide (HY-17364)-induced activation of p53.
分子量

447.53

Formula

C26H29N3O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

K34c 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

K34c939769-93-4IntegrinU87MGglioblastomaα5β1 integrinInhibitorinhibitorinhibit

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产品名称：
K34c
目录号：
HY-150124
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