2. Immunology/Inflammation
  3. Kallikrein
  4. Kallikrein 5-IN-2 TFA

Kallikrein 5-IN-2 TFA 是 Kallikrein 5-IN-2 (HY-148949) 的 TFA 盐形式。Kallikrein 5-IN-2 TFA 是 kallikrein 5 (KLK5) 的选择性抑制剂，pIC50 为 7.1。Kallikrein 5-IN-2 TFA 无光毒性 (100 μg/mL) 且无刺激性。Kallikrein 5-IN-2 在 pH 4-pH 8 的非氧化环境中保持稳定。Kallikrein 5-IN-2 有潜力改善 Netherton 综合征。

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Kallikrein 5-IN-2 TFA Chemical Structure

Kallikrein 5-IN-2 TFA Chemical Structure

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Kallikrein 5-IN-2 TFA 的其他形式现货产品:

Customer Review

Other Forms of Kallikrein 5-IN-2 TFA:

Kallikrein 5-IN-2 TFA 相关抗体

Top Publications Citing Use of Products

查看 Kallikrein 亚型特异性产品:

查看所有亚型
KLK1 KLK5 KLK8 KLK14 KLKB1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kallikrein 5-IN-2 TFA is the TFA salt form of Kallikrein 5-IN-2 (HY-148949). Kallikrein 5-IN-2 TFA is a selective inhibitor for kallikrein 5 (KLK5) with pIC50 of 7.1. Kallikrein 5-IN-2 TFA is non-phototoxic (100 μg/mL) and non-irritant. Kallikrein 5-IN-2 is stable at pH 4-pH 8 under non-oxidative condition. Kallikrein 5-IN-2 is potent in ameliorating the Netherton syndrome[1].

IC50 & Target

KLK5

7.1 (pIC50)

KLK8

6.1 (pIC50)

KLK14

5.4 (pIC50)

KLKB1

5.2 (pIC50)

KLK1

4.2 (pIC50)

分子量

512.48

Formula

C25H23F3N6O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Kallikrein 5-IN-2 TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kallikrein 5-IN-2KallikreinKLKKallikrein-related peptidaseNetherton syndromeselectiveInhibitorinhibitorinhibit

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产品名称：
Kallikrein 5-IN-2 TFA
目录号：
HY-148949A
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