2. Cell Cycle/DNA Damage Cytoskeleton
  3. Kinesin
  4. Kolavenic acid analog

Kolavenic acid analog  (Synonyms: KAA)

目录号: HY-146146
产品使用指南 技术支持

Kolavenic acid analog (KAA) 是一种抗癌剂。Kolavenic acid analog 对 HSET 过量生产的酵母细胞具有很强的活性。在含有高 HSET 水平和超数中心体的人类癌细胞中，Kolavenic acid analog 抑制中心体聚集。

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Kolavenic acid analog Chemical Structure

Kolavenic acid analog Chemical Structure

CAS No. : 2379777-37-2

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Kolavenic acid analog 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kolavenic acid analog (KAA) is an anticancer agent. Kolavenic acid analog shows strong activity against HSET-overproducing yeast cells. Kolavenic acid analog inhibits centrosome clustering in human cancer cells containing high HSET levels and supernumerary centrosomes[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MDA-MB-231 IC50
81.9 μM
Compound: 2; KAA
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
[PMID: 31753800]
WI-38 IC50
100 μM
Compound: 2; KAA
Antiproliferative activity against human WI38 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human WI38 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
[PMID: 31753800]
分子量

402.57

Formula

C25H38O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Kolavenic acid analog 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kolavenic acid2379777-37-2KAAKinesinHSET/KIFC1MDA-MB-231anticancerInhibitorinhibitorinhibit

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