2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. KOR/DOR agonist 1

KOR/DOR agonist 2 是一种 KOR 和 DOR 阿片受体激动剂，Ki 值分别为 0.14 nM 和 0.93 nM。KOR/DOR agonist 2 表现出显著的抗伤害作用。KOR/DOR agonist 2 可穿透血脑屏障。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KOR/DOR agonist 1 Chemical Structure

KOR/DOR agonist 1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

KOR/DOR agonist 1 相关抗体

Top Publications Citing Use of Products

查看 Opioid Receptor 亚型特异性产品:

查看所有亚型
μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KOR/DOR agonist 2 is a KOR and DOR opioid receptors agonist with Ki values of 0.14 nM, and 0.93 nM, respectively. KOR/DOR agonist 2 shows significant antinociceptive effects. KOR/DOR agonist 2 penetrates the blood-brain barrier[1].

IC50 & Target[1]

κ Opioid Receptor/KOR

0.14 nM (Ki)

δ Opioid Receptor/DOR

0.2 nM (Ki)

μ Opioid Receptor/MOR

0.93 nM (Ki)

体外研究
(In Vitro)

KOR/DOR agonist 2（化合物 21）与 MOR 的结合力为亚纳摩尔，Ki 值为 0.20 nM[1]。
在 [35S]-GTPγS 结合试验中，KOR/DOR agonist 2 在 KOR、MOR 和 DOR 处表现出功能活性，EC50 值分别为 0.04 nM、0.58 nM、1.28 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

KOR/DOR agonist 1 相关抗体:
体内研究
(In Vivo)

KOR/DOR agonist 2（0.1 mg/kg；皮下注射；一次）在温水尾浸试验中产生显著的抗伤害作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Swiss Webster mice (6-8 week-old)[1]
Dosage: 0.1 mg/kg
Administration: Subcutaneous injection; once
Result: Showed significant antinociceptive effects.
分子量

476.56

Formula

C28H32N2O5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

KOR/DOR agonist 1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KOR/DOR agonist 1Opioid ReceptorKOR/DOR agonistantinociceptive effectsblood-brain barrieInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
KOR/DOR agonist 1
目录号：
HY-162552
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z