1. Stem Cell/Wnt
  2. β-catenin Wnt
  3. KP-6

KP-6 是一种多肽,是一种 Wnt/β-catenin 信号抑制剂。KP-6 抑制 TGF-β 并阻断体内至关重要的快速纤维化信号通路。KP-6 抑制肾组织损伤和肾纤维化,逆转慢性肾病(CKD)的病程。

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KP-6 Chemical Structure

KP-6 Chemical Structure

CAS No. : 2102414-23-1

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规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KP-6, a polypeptide, is a Wnt/β-catenin signal inhibitor. KP-6 inhibits TGF-β and blocks rush fibrosis signal path crucial in vivo. KP-6 suppresses Renal tissues damage and renal fibrosis, and reverse the course of disease of chronic kidney disease (CKD)[1].

分子量

3491.83

Formula

C159H232N46O44

CAS 号
Sequence

Gln-Pro-Val-Val-Thr-Leu-Tyr-His-Trp-Asp-Leu-Pro-Gln-Arg-Leu-Gln-Asp-Ala-Tyr-Gly-Gly-Trp-Ala-Asn-Arg-Ala-Leu-Ala-Asp-His

Sequence Shortening

QPVVTLYHWDLPQRLQDAYGGWANRALADH

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
KP-6
目录号:
HY-P6441
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