1. GPCR/G Protein MAPK/ERK Pathway Apoptosis
  2. Ras Apoptosis
  3. KRAS G12C inhibitor 63

KRAS G12C inhibitor 63 (K45) 是一种 KRAS G12C 抑制剂。KRAS G12C inhibitor 63 可诱导细胞凋亡 (Apoptosis). KRAS G12C inhibitor 63 具有抗肿瘤活性。

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KRAS G12C inhibitor 63 Chemical Structure

KRAS G12C inhibitor 63 Chemical Structure

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查看 Ras 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KRAS G12C inhibitor 63 (K45) is a KRAS G12C inhibitor. KRAS G12C inhibitor 63 can induce Apoptosis. KRAS G12C inhibitor 63 has antitumor activity[1].

体外研究
(In Vitro)

KRAS G12C inhibitor 63 对携带 KRAS-G12C 的 NCI-H23 和 NCI-H358 癌细胞表现出较强的抗增殖能力,IC50 值分别为 0.77 μM 和 1.50 μM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

511.40

Formula

C27H24Cl2N2O4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
KRAS G12C inhibitor 63
目录号:
HY-163720
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