2. Immunology/Inflammation
  3. Interleukin Related
  4. KRN7000 analog 3

KRN7000 analog 3 (Compound 14)，一种 α-GalCer (HY-102022) 类似物，是一种 iNKT 激动剂。KRN7000 analog 3 在 mNK1.2 细胞中诱导的 IL-2 细胞因子分泌水平 (49.2-62.6 ng/mL) 高于 α-GalCer (44.1 ng/mL)。KRN7000 analog 3 有望用于抗肿瘤剂和疫苗佐剂的研究。

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KRN7000 analog 3 Chemical Structure

KRN7000 analog 3 Chemical Structure

CAS No. : 1384423-78-2

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KRN7000 analog 3 相关抗体

Top Publications Citing Use of Products

查看 Interleukin Related 亚型特异性产品:

查看所有亚型
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KRN7000 analog 3 (Compound 14),α-GalCer (HY-102022) analogue, is a iNKT agonist. KRN7000 analog 3 induces higher levels of IL-2 cytokine secretion (49.2-62.6 ng/mL) than a-GalCer (44.1 ng/mL) in mNK1.2 cells. KRN7000 analog 3 is promising for research of antitumor agents and vaccine adjuvants[1].

IC50 & Target

IL-2

 

分子量

816.11

Formula

C47H77NO10
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

KRN7000 analog 3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRN7000 analog 31384423-78-2Interleukin RelatedILα-GalCer analogueIL-2 cytokineInhibitorinhibitorinhibit

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产品名称：
KRN7000 analog 3
目录号：
HY-159902
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