1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. KWWCRW

KWWCRW 是一种 Holliday 连接体抑制肽,具有抗癌活性。KWWCRW 通过与反应的 Holliday 连接体的中间体结合并阻止其分解来抑制 DNA 修复过程中的同源重组修复 (HDR),并抑制噬菌体在体外进行位点特异性重组。

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KWWCRW Chemical Structure

KWWCRW Chemical Structure

CAS No. : 292148-25-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KWWCRW is a Holliday linker inhibitory peptide with anticancer activity. KWWCRW inhibits homologous recombination repair (HDR) during DNA repair by binding to the reactive Holliday linker intermediate and preventing its degradation, and inhibits site-specific recombination by bacteriophage in vitro[1].

分子量

964.15

Formula

C48H61N13O7S

CAS 号
Sequence

Lys-Trp-Trp-Cys-Arg-Trp

Sequence Shortening

KWWCRW

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
KWWCRW
目录号:
HY-P4161
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