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KY 234 是一种口服有效、靶向血栓素 A2 生成的抑制剂,IC50 为 5 μM。KY 234 对白三烯 D4 (LTD4)、组胺和抗原诱导的豚鼠支气管收缩有显著抑制作用,IC50 分别为 6.0 mg/kg,2.5 mg/kg,6.3 mg/kg。

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KY 234 Chemical Structure

KY 234 Chemical Structure

CAS No. : 172544-75-1

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  • 生物活性

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生物活性

KY 234 is an orally effective inhibitor that targets thromboxane A2 production, with an IC50 of 5 μM. KY 234 significantly inhibits leukotriene D4 (LTD4), histamine, and antigen-induced bronchoconstriction in guinea pigs, with IC50 values of 6.0 mg/kg, 2.5 mg/kg, and 6.3 mg/kg, respectively[1].

IC50 & Target

Thromboxane A2 receptor[1]

分子量

555.65

Formula

C33H34N5NaO2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

KY 234 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
KY 234
目录号:
HY-117842
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