L-Arginine-¹⁵N₄,d₇ hydrochloride  (Synonyms: (S)-(+)-Arginine-¹⁵N₄,d₇ hydrochloride)

L-Arginine-¹⁵N₄,d₇ (hydrochloride) is the deuterium and ¹⁵N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

221.68

C₆H₈D₇Cl¹⁵N₄O₂

1119-34-2

L-精氨酸 ¹⁵N₄,d₇ (盐酸)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief]