1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Aspartic acid-13C4

L-Aspartic acid-13C4  (Synonyms: L-天门冬氨酸 13C4)

目录号: HY-N0666S4 纯度: 98.30%
COA 产品使用指南

L-Aspartic acid-13C4 是带有 13C 标记的 L-Aspartic acid。L-Aspartic acid 是一种氨基酸,被证明是一种结肠特异性活性分子输送的前体活性分子。

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L-Aspartic acid-<sup>13</sup>C<sub>4</sub> Chemical Structure

L-Aspartic acid-13C4 Chemical Structure

CAS No. : 55443-54-4

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Other Forms of L-Aspartic acid-13C4:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

L-Aspartic acid-13C4 is the 13C-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 EC50
15 μM
Compound: 5960
Substrate uptake by the Excitatory Amino Acid Transporter 1 (EAAT1, SLC1A3) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC1A3 cells
Substrate uptake by the Excitatory Amino Acid Transporter 1 (EAAT1, SLC1A3) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC1A3 cells
10.5281/zenodo.6782621
HEK293 EC50
398 μM
Compound: L-asp
Inhibition of the Excitatory Amino Acid Transporter 1 (EAAT1, SLC1A3) as assessed by a phenotypic impedance-based assay detecting changes in cell morphology by L-glutamate uptake in HEK-293 JumpIN-SLC1A3 cells
Inhibition of the Excitatory Amino Acid Transporter 1 (EAAT1, SLC1A3) as assessed by a phenotypic impedance-based assay detecting changes in cell morphology by L-glutamate uptake in HEK-293 JumpIN-SLC1A3 cells
[PMID: 35677430]
体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

137.07

Formula

13C4H7NO4

CAS 号
非标记 CAS
性状

固体

颜色

White to off-white

中文名称

L-天门冬氨酸 13C4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: 98.30%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
L-Aspartic acid-13C4
目录号:
HY-N0666S4
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