1. Others Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Calcium Channel iGluR Endogenous Metabolite
  3. L-Phenylalanine-d

L-Phenylalanine-d  (Synonyms: (S)-2-Amino-3-phenylpropionic acid-d1)

目录号: HY-N0215S13
产品使用指南

L-Phenylalanine-d 是 L-Phenylalanine 的氘代物。L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) 是分离自大肠杆菌的必需氨基酸。L-Phenylalanine 是一种电压依赖性 α2δ 亚基 Ca2+ 通道拮抗剂,Ki 为 980 nM。L-Phenylalanine 是 NMDARs (KB 573 μM) 和非 NMDARs 的甘氨酸和谷氨酸结合位点的竞争性拮抗剂。L-Phenylalanine 广泛用于食品香料和药品的生产中。

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L-Phenylalanine-d Chemical Structure

L-Phenylalanine-d Chemical Structure

CAS No. : 54793-54-3

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Other Forms of L-Phenylalanine-d:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

L-Phenylalanine-d is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

IC50 & Target

NMDA Receptor

 

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

166.20

Formula

C9H10DNO2

CAS 号
非标记 CAS

63-91-2

中文名称

L-苯丙氨酸 d1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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