2. Stem Cell/Wnt TGF-beta/Smad
  3. TGF-beta/Smad
  4. Landogrozumab

Landogrozumab  (Synonyms: 兰洛珠单抗; LY2495655; Anti-GDF8 / Myostatin Reference Antibody (landogrozumab))

目录号: HY-P99370 纯度: 99.54%
COA 技术支持

Landogrozumab (LY2495655) 是一种人源化抗肌肉生长抑制素单克隆抗体。Landogrozumab 可有效改善肌肉体积、握力和功能。Landogrozumab 可用于肌肉萎缩疾病的相关研究。

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CAS No. : 1391726-30-9

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规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥7800
In-stock
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50 mg   询价  

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Landogrozumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Landogrozumab (LY2495655) is an humanized anti-myostatin monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease[1].

同型

Human IgG4 kappa
推荐同型对照抗体
种属

Humanized
体内研究
(In Vivo)

Landogrozumab (3 和 15 mg/kg；静脉注射 1 次) 影响杜氏肌营养不良老年小鼠的肌肉质量[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Duchenne muscular dystrophy (DMD) C57BL/10-mdx mouse model[1]
Dosage: 3 and 50 mg/kg
Administration: Intravenous injection; 3 and 50 mg/kg once
Result: Increasesd muscle mass of aged mice at a dose of 50 mg/kg while 3 mg/kg showed no significant effects.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

兰洛珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
纯度 & 产品资料
参考文献

Landogrozumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Landogrozumab1391726-30-9LY2495655 Anti-GDF8 / Myostatin Reference Antibody (landogrozumab)兰洛珠单抗LY 2495655LY-2495655TGF-beta/SmadTransforming growth factor betamuscle volumehand grip strengthmuscle wastingmuscle massmiceduchenne muscular dystrophyInhibitorinhibitorinhibit

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