1. Anti-infection
  2. Antibiotic
  3. Lankacidinol

Lankacidinol  (Synonyms: T-2636 F)

目录号: HY-117183
产品使用指南

Lankacidinol (T-2636 F) 是一种抗生素。Lankacidinol 及其相关代谢物 2,18-seco-lankacidinol A(1)和 2,18-seco-lankacidinol B(2)具有显著的生物活性和潜在的药用价值。同时,2,18-seco-lankacidinol A 表现出强效的抗肿瘤活性。

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Lankacidinol Chemical Structure

Lankacidinol Chemical Structure

CAS No. : 23498-37-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lankacidinol (T-2636 F) is an antibiotic. Lankacidinol and its related metabolites 2,18-seco-lankacidinol A (1) and 2,18-seco-lankacidinol B (2) have significant biological activities and potential medicinal value. In addition, 2,18-seco-lankacidinol A exhibits potent antitumor activity.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 100 μM
Compound: 3
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 34883453]
HeLa IC50
24.8 μM
Compound: 3
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 34883453]
MCF7 IC50
75.7 μM
Compound: 3
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 34883453]
分子量

461.55

Formula

C25H35NO7

CAS 号
初始来源

Streptomyces sp.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Lankacidinol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HY-117183
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