2. Anti-infection
  3. Bacterial
  4. LasR-IN-2

LasR-IN-2 是一种 LasR 抑制剂，可与 TRY-56 残基形成氢键。LasR-IN-2 可用于细菌感染，中性粒细胞减少症、严重烧伤和囊性纤维化 (CF) 慢性肺病的研究。

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LasR-IN-2 Chemical Structure

LasR-IN-2 Chemical Structure

CAS No. : 3033530-61-6

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LasR-IN-2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LasR-IN-2 is a LasR inhibitor that forms H-bonding with TRY-56 residue. LasR-IN-2 can be used in the research of bacterial infection, neutropenia, severe burns and chronic lung disease in cystic fibrosis (CF)[1].

IC50 & Target

LasR[1]
体外研究
(In Vitro)

LasR-IN-2 (Compound 8a, 4.68-150 μg/mL, 24 h) inhibits P. aeruginosa growth[1].
LasR-IN-2 (18.5 μM, 24 h) inhibits biofilm formation, pyocyanin production, and rhamnolipids production[1].
LasR-IN-2 (24 h) inhibits human dermal fibroblasts (HDFa) growth with an IC50 value of 102 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

LasR-IN-2 相关抗体:

Cell Viability Assay[1]

Cell Line: P. aeruginosa (ATCC27853)
Concentration: 4.68-150 μg/mL
Incubation Time: 24 h
Result: Inhibited bacterial growth with a MIC value of 74.40 μM.
分子量

377.82

Formula

C21H16ClN3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LasR-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LasR-IN-23033530-61-6BacterialInfectionGram-negativeP. aeruginosaHDFafibroblastbiofilm formationInhibitorinhibitorinhibit

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目录号：
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